氟喹诺酮类抗菌药适用于敏感菌所致的尿路感染、淋病、前列腺炎、肠道感染和伤寒及其他沙门菌感染。
目的：探讨氟喹诺酮类抗菌药后效应及其合理应用。
OBJECTIVE:To probe into the after-effects and rational use of fluroquinoloncs.
随着氟喹诺酮类抗菌药在临床广泛应用，肠球菌对其耐药性迅速增长。
Increasing resistance to FQs in enterococci has been noted with these agents broadly used in clinical medicine.
肠球菌对氟喹诺酮类抗菌药的耐药机制主要为靶位改变和药物主动外排导致的细胞内药物积聚减少。
The main two mechanisms of FQs resistance in enterococci are alterations in the targets of FQs and decreased intra-cellular drugs accumulation resulting from active excretion of drug.
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