目的:介绍环氧酶- 2抑制剂药物的临床应用进展,以期为临床医师、药师提供参考。
OBJECTIVE: to introduce the progress in the clinical application of epoxidase-2 inhibitors for references of clinician and pharmacists.
目的探讨选择性及非选择性环氧合酶-2抑制剂(COX-2)对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
为了观察坐骨神经损伤(SNI)后小鼠全脑环氧合酶(COX) - 1和COX - 2的表达变化,以及不同选择性的COX抑制剂对SNI所致神经病理性痛的效应。
To observe the expression of cyclooxygenase (COX) -1 and COX-2 in brain after spared nerve injury (SNI) and compare the analgesic effects of COX inhibitors with different selectivity.
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