手性芳香胺是药物合成的重要中间体,同时也可用作手性助剂及手性拆分剂。
Optically pure arylamines are important building blocks in drug synthesis and are commonly used as chiral auxiliaries and chiral resolving agents.
目的:建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。
Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.
结果表明被研究的手性农药戊唑醇在正丁醇作流动相极性改性剂时拆分效果较好。
The results indicate that the pesticide tebuconazole has a relatively good effect on enantiomeric separation and retention of tebuconazole.
应用推荐