手性芳香胺是药物合成的重要中间体,同时也可用作手性助剂及手性拆分剂。
Optically pure arylamines are important building blocks in drug synthesis and are commonly used as chiral auxiliaries and chiral resolving agents.
目的:建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。
Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.
结果表明被研究的手性农药戊唑醇在正丁醇作流动相极性改性剂时拆分效果较好。
The results indicate that the pesticide tebuconazole has a relatively good effect on enantiomeric separation and retention of tebuconazole.
本论文的第三至第六部分介绍了高效液相色谱手性流动相添加剂法拆分麻黄碱、对羟基苯甘氨酸甲酯、美托洛尔、布洛芬对映体。
In part III to VI, ephedrine, tyrosine methyl ester, metoprolol, ibuprofen enantiomeric separation with chiral additive as mobile phase by high performance liquid chromatography are presented.
以手性苯甘氨酸丁酯为拆分剂的方法操作简单、收率较高,适于工业化生产。
The method of using optically active phenylglycine butyl ester as resolution agent can obtain the higher yield, and it is easy to operate. So it is suitable for industrial production.
化学方法包括手性辅剂诱导、手性氧化剂氧化、手性拆分和不对称催化等。
The chemical methods include chiral auxiliary's induction, chiral oxidant'soxidation, chiral resolution, and enantioselective catalysis.
本课题的研究内容是方便、简单地合成手性前体hpba,采用化学拆分法制备手性化合物(R) - HPBA,并进行使用手性相转移催化剂不对称合成(?)
In this paper, we expediently, simply synthesized the racemic HPBA, prepared (r) -hpba which using chemical resolution and were engaged in studying the asymmetric synthesis of (?)
本课题的研究内容是方便、简单地合成手性前体hpba,采用化学拆分法制备手性化合物(R) - HPBA,并进行使用手性相转移催化剂不对称合成(?)
In this paper, we expediently, simply synthesized the racemic HPBA, prepared (r) -hpba which using chemical resolution and were engaged in studying the asymmetric synthesis of (?)
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