复制慢性温和不可预知应激抑郁模型(CUMS),造模3周恢复1周后无菌收集回肠、盲肠和结肠内容物,利用ERIC-PCR技术比较肠道不同部位菌群多态性结构,分析抑郁模型大鼠及逍遥散干...
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目的(1)建立大鼠慢性温和不可预知应激抑郁模型(Chronic unpredictable mild stress, CUMS),并进行行为学评价。观察睡眠剥夺、氯丙咪嗪及两者联合对抑郁模型大鼠行为学的影响。
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慢性应激抑郁模型 chronic stress induced depression model ; depression ; Chronic stress of depression model
方法：采用大鼠慢性应激抑郁模型、灌胃给药、行为学及免疫组织化学方法。
METHOD: This study adapted the depression rat model of chronic stress, behavior and immunohistochemistry.
目的观察复方刺蒺藜苷对慢性轻度不可预见性应激抑郁模型大鼠行为学的影响。
Objective:To observe the effect of tribuloside on behavior and neurogenesis in dentate gyrus of chronic stress depression rats.
方法：以多种复合刺激交替进行的方法建立慢性应激抑郁模型，并取脾脏进行淋巴细胞体外培养。
Methods:Chronic stress of depression model was made by alternate mulriple stimulate, and lymphocyte of spleen was cultured in vitro.
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