方法:采用大鼠慢性应激抑郁模型、灌胃给药、行为学及免疫组织化学方法。
METHOD: This study adapted the depression rat model of chronic stress, behavior and immunohistochemistry.
目的观察复方刺蒺藜苷对慢性轻度不可预见性应激抑郁模型大鼠行为学的影响。
Objective:To observe the effect of tribuloside on behavior and neurogenesis in dentate gyrus of chronic stress depression rats.
方法:以多种复合刺激交替进行的方法建立慢性应激抑郁模型,并取脾脏进行淋巴细胞体外培养。
Methods:Chronic stress of depression model was made by alternate mulriple stimulate, and lymphocyte of spleen was cultured in vitro.
在应激性抑郁研究中,常用的动物模型包括行为绝望模型、习得无助模型、慢性应激模型等。
Animal models of Behavioral Despair, Learned Helplessness, and Chronic stress, etc., are widely used to study stress-induced depression.
方法采用慢性综合应激法建立抑郁大鼠模型。
Methods Rat was treated with chronic and comprehensive stress to form depression model.
结论在脑出血的基础上给予慢性不可预见的温和应激,能建立较理想的脑出血后抑郁动物模型。
Conclusion It is an ideal method for establishing the animal model of post-encephalorrhagia depression to give chronic unpredictable mild stress to rats on the basis of cerebral hemorrhage.
应用分养和长期不可预见性中等强度应激造成抑郁症模型大鼠。
Separation feeding, long term unpredictability and medium stimulation stress techniques were applied to develop depression model rats.
模型制备:采用慢性不可预见性应激法造成大鼠抑郁模型。
Model preparation: The depression model rat was produced by chronic unpredictable stress.
方法:(1) 动物模型:连续21天慢性轻度不可预见性应激配合孤养方法建立大鼠抑郁模型。
METHODS: (1) The chronic stressed depression rats were established by chronic unpredictable mild stress and separation after 21 days.
在慢性应激大鼠抑郁症模型中,甘丙肽及其受体2在部分脑区的高表达提示甘丙肽很有可能参与了应激过程中神经元功能的调制。
The high expression of galanin and galanin receptor-2 in some brain area suggested that galanin probably take part in the modulation of the function of neurons during the stress process.
而慢性应激是抑郁症的主要发病诱因,慢性应激抑郁症模型被公认为是研究抑郁症的理想模型。
Chronic stress is the primary inducement for depression. Chronic mild stress model is a idea model for the study of depression.
而慢性应激是抑郁症的主要发病诱因,慢性应激抑郁症模型被公认为是研究抑郁症的理想模型。
Chronic stress is the primary inducement for depression. Chronic mild stress model is a idea model for the study of depression.
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