目的：对炭疽毒素保护性抗原（PA）的不同结构域进行了缺失突变，以期找到免疫原性降低而功能变化不大的PA蛋白突变体。
Objective:To find protective antigen(PA) defective mutants of anthrax toxin with the same function as PA but with low immunogenicity, different domains of PA were mutated.
为了阐明BRD-7基因的作用机制，我们首先对其溴区结构域进行了初步的研究。
In order to clarify the function mechanism of this gene, we investigate an important motif of BRD 7, the bromodomain.
为此我们对蛋白质序列进行了结构域的划分和映射，并采用机器学习的方法提取出结构域之间的相互作用。
We then used a machine learning approach to deduce a protein interaction map that is most consistent with the underlying domain information.
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