数学模型；围生儿；出生缺陷率；拟合。
Mathematical model; Perinatal infants; Birth defects rate; Fitting.
对近五年有关出生缺陷的中外文献进行回顾和分析，了解出生缺陷率的变化趋势。
We review articles about birth defect in recent 5 years to analysis the birth defect trend in these years.
“这种检测的理念有可能提高出生率，最大程度的减小流产和因为染色体不规则而导致的先天性缺陷。”Fishel说。
"This screening method has the potential to improve birth rates, minimise the incidence of miscarriage and birth defects caused by chromosomal irregularity," Fishel said.
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