数学模型；围生儿；出生缺陷率；拟合。
Mathematical model; Perinatal infants; Birth defects rate; Fitting.
对近五年有关出生缺陷的中外文献进行回顾和分析，了解出生缺陷率的变化趋势。
We review articles about birth defect in recent 5 years to analysis the birth defect trend in these years.
“这种检测的理念有可能提高出生率，最大程度的减小流产和因为染色体不规则而导致的先天性缺陷。”Fishel说。
"This screening method has the potential to improve birth rates, minimise the incidence of miscarriage and birth defects caused by chromosomal irregularity," Fishel said.
在妥泰联用抗癫痫药丙戊酸盐的女性中出生缺陷发生率最高，后者已被许多研究结果和癫痫数据库认定与出生缺陷相关。
The birth defect rate was highest among women who took Topamax in combination with the epilepsy drug valproate, which has been linked to birth defects in numerous studies and epilepsy databases.
目的了解1990 ~ 1999年湖南省安仁县出生缺陷发病率的动态变化趋势及流行病学特征。
Objective To study the variation trend on the incidence and epidemiological characteristics of birth defects during the period from 1990 through 1999 in Anren County.
加强孕期保健知识教育，对降低出生缺陷生率具有重要意义。
It is of significance to enhance the health knowledge and education during pregnancy for lower the incidence rate of birth defects.
目的：探明围生儿出生缺陷的种类和发生率，寻找影响出生缺陷的可能因素。
Objective: to probe into the varieties and incidence of perinatal birth defects and its potential complications.
结论出生缺陷的产前筛查结合产前诊断对降低出生缺陷的出生率有重要意义。
Conclusion: Combination of prenatal screening and diagnosis for birth defects is important to reduce the birth rate of birth defects.
出生缺陷；监测；发生率；干预措施。
结论加强围产保健宣传、健全农村基层妇幼保健网和提高孕产妇保健意识是降低出生缺陷发生率的有效措施。
Conclusion to strengthen perinatal health education, to improve consciousness of maternal health care are effective measures to decrease the birth defect rate.
目的：了解三峡中东部区域(宜昌市)0 ~ 7岁儿童出生缺陷的发生率及其分布情况。
AIM: To investigate the incidence rate and distribution of birth defects among children of 0-7 years old in the Middle East region of Three Gorges (Yichang city).
结论：我省1997到2004年出生缺陷监测出生缺陷总发生率和神经管畸形发生率均呈逐年下降趋势，且下降幅度基本一致。
Conclusion: From 1997 to 2004, the comprehensive occurrence possibility and Nerve Tube Defects (NTDs) occurrence possibility appear a decrease trend year by year, moreover, the scope keep the same.
目的分析南海区0 ~5岁儿童出生缺陷发生率、种类、分布特征。
Objective: To investigate the incidence, kind, and distribution features of children with birth defects at 0 ~ 5 years old in Nanhai district.
提示：高龄孕妇应做羊水afp筛查检测，有助于提高神经管缺陷患儿的诊出率，避免患儿出生。
Hint: For the older pregnant woman, the AFP in amniotic fluid should be checked as a rule. The check rate of nerve tube blemish can be increased, and the birth of ill infant can be avoided.
神经管缺陷儿出生素质差，围产期病死率高，预后不良。
Babies with NTDs are in poor birth quality, higher perinatal mortality and poor prognosis.
出生缺陷发生率随着孕产次的增加而明显提高。
The prevalence rates increased with increasing gravidity or parity.
结果：危险人群胎儿的出生缺陷发病率为15 7% ，明显高于对照组（P< 0 .0 0 1）。
Results:Incidence of birth defects is 15.7% in the risk population , distinct higher than contrast group (P<0.001).
农村出生缺陷的发生率高于城市。
目的探讨出生缺陷的产前检查及干预措施，从而降低其发生率。
Objective to discuss the prenatal diagnosis of birth defects and the intervention measures so as to reduce the incidence.
其中神经管缺陷发病率最高，是严重影响出生人口素质，导致先天性残疾的主要病因之一。
Neural tube defects had a high incidence, seriously influenced the birth - population diathesis and disabled.
其中神经管缺陷发病率最高，是严重影响出生人口素质，导致先天性残疾的主要病因之一。
Neural tube defects had a high incidence, seriously influenced the birth - population diathesis and disabled.
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