首先，威尼斯在亚得里亚海的中介功能被直接贸易所取代。威尼斯在该海域曾主导着其他国家的航运业务。

First, Venice's intermediary functions in the Adriatic Sea, where it had dominated the business of shipping for other parties, were lost to direct trading.

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它提供了位置、协议和一系列中介功能。

It provides location, protocol, and a number of mediation capabilities.

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它还提供了消息中介功能，包括服务端点路由。

It also provides the message mediation capabilities including service endpoint routing.

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