综上所述，药物转运体及细胞色素P450酶（CYP450）是机体的重要清除系统，而编码它们的遗传基因普遍存在多态性，其中某些多态性能够改变蛋白质的表达和功能，从而影响到转运体及C四...
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CYP450 inducer CYP450诱导剂
CYP450 isoenzyme 细胞色素氧化酶P450异构酶
CYP450 isoenzymes CYP450同工酶
CYP450 hydroxylase CYP450羟基化酶
Content of CYP450 CYP450含量
Results: Single dose of DEX made mild liver toxicity by inducing CYP450.
结果：单独DEX诱导具有轻微的肝脏毒性。
Oxidative stress after PH can not only impede hepatocellular proliferation, but also damage liver microsomal CYP450.
PH引起的氧化应激和炎症因子不仅阻碍肝细胞增殖，还可损伤肝微粒体CYP450酶。
To evaluate the activity of CYP450 in different groups, the metabolic rate of cocktail probe drugs was determined by HPLC.
通过高效液相色谱法检测探针药物的代谢率，评价各组CYP450酶的活性水平。
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