Results: Single dose of DEX made mild liver toxicity by inducing CYP450.
结果：单独DEX诱导具有轻微的肝脏毒性。
Oxidative stress after PH can not only impede hepatocellular proliferation, but also damage liver microsomal CYP450.
PH引起的氧化应激和炎症因子不仅阻碍肝细胞增殖，还可损伤肝微粒体CYP450酶。
To evaluate the activity of CYP450 in different groups, the metabolic rate of cocktail probe drugs was determined by HPLC.
通过高效液相色谱法检测探针药物的代谢率，评价各组CYP450酶的活性水平。
And the liver microsome protein content, CYP450 content and erythromycin-N-demethylase activity appear some gender differences.
同时肝微粒体蛋白含量、CYP450含量和红霉素-N-脱甲基酶活性呈现有一定的性别差异。
CYP450 is regulated by genetic genes. Once the gene mutates, the CYP450 enzyme that coded and the drug metabolism then will change.
CYP450的合成受着遗传基因的调控，一旦基因发生变异，它所调控合成的CYP450酶及酶所催化的药物代谢即发生变化。
Cytochrome P450 (CYP450) is the crucial metabolizing enzymes in the bodies. It is the most important effect for drug metabolization.
细胞色素P 450 (CYP450)是机体药物代谢的关键酶，在药物生物转化中起着重要作用。
Table 1 presented the current inventory of Recombinant CYP450 Enzymes and their price, which is qualified and useful tools for identifying the metabolism pathway (s).
Cype x产重组CYP450纯酶在本公司的现货库存和价目见表1。该产品为用于代谢途径鉴定的良好工具。
Methods: the binding rate of DCPB to plasma protein was determined by equilibrium dialysis method, and the content of CYP450 was assayed by differential spectrum method.
方法：用分光光度法测定cyp450含量，用平衡透析法测定蛋白结合率。
A rapid in vitro assessment of CYP450 induction and inhibition is a part of the current paradigms for identifying drug substances likely to be metabolized via such interactions.
目前确定候选药物出现此类相互作用可能性的主要方法是通过体外CYP450诱导和抑制潜能的快速筛选。
A rapid in vitro assessment of CYP450 induction and inhibition is a part of the current paradigms for identifying drug substances likely to be metabolized via such interactions.
目前确定候选药物出现此类相互作用可能性的主要方法是通过体外CYP450诱导和抑制潜能的快速筛选。
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