Pre-oxidation process in the first dehydrogenation reaction,cyclization reaction happen behind it.
在预氧化过程中首先发生的脱氢反应,再发生环化反应。 二元组分和三元组成预氧化过程都是先发生脱氢,后发生环化反应。
参考来源 - 共聚单体对PAN共聚物及原丝和预氧丝结构和性能的影响Finally, the process conditions of cyclization reaction was researched and analyzed, and the optimized conditions are obtained. Under the suitable conditions, the yield reached 77%.
最后对环合反应的工艺参数进行了研究和分析,确定了工艺优化条件,在优化条件下,环合反应的收率可以达到77%。
参考来源 - 呋喃酚合成工艺优化·2,447,543篇论文数据，部分数据来源于NoteExpress
A possible mechanism for the cyclization reaction was suggested.
提出了可能的环化反应机理。
The appropriate reaction conditions of cyclization reaction: NaOEt was 1.4 mole eq.
合环反应的条件为：乙醇钠的用量为1.4摩尔当量；
Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
筛选以2 -溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
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