A possible mechanism for the cyclization reaction was suggested.
提出了可能的环化反应机理。
The appropriate reaction conditions of cyclization reaction: NaOEt was 1.4 mole eq.
合环反应的条件为：乙醇钠的用量为1.4摩尔当量；
Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo- butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Large amounts of methanol and ethanol exist in the effluent of the condensation and cyclization reaction during the trimethoprim synthesis process. A new recovery process was evaluated experimentally.
甲氧苄氨嘧啶合成过程产生大量含甲醇和乙醇的废液，实验研究了新的回收工艺。
The cracking and skeletal isomerization became more strong with the rise of reaction temperature, while oligomerization, cyclization and hydrogen transfer reaction became weaker.
随着反应温度的提高，裂化反应和骨架异构化反应增强，但齐聚反应、氢转移反应和环化反应减弱。
The conditions of reaction of cyclization were moderate, the purity and yield of the product was higher.
环合反应的条件缓和，产品收率和纯度高，在四氢咔唑类化合物的化学制备中具有重要参考价值。
The mechanism was discussed in the proton acid catalytic reaction of furan phenol cyclization.
探讨了呋喃酚环合反应质子酸催化机理。
METHODS: The title compounds were synthesized by acylation of twelve acyl chlorides and two intermediates prepared by Friedel Crafts reaction, lengthening of carbon chain, hydrolysis and cyclization;
方法：通过付克反应、碳链延长、水解和环合反应得到两个关键中间体，然后通过酰化反应制得各种酰胺化合物；
By adjusting the reaction temperature or using different cyclization methods, condensation is carried out, and indanone dimmer and indanone trimer can be obtained respectively.
然后进行缩合，通过调节反应温度或者使用不同的环化方法，可分别得到茚酮的二聚物及三聚物。
Methods Apraclonidine was synthesized from P-Nitraniline by reaction with reduction, adding protection group, formylation, chlorination, cyclization, off-protecting group.
方法采用对硝基苯胺为原料，经还原、加保护基、甲酰化、氯化、环合、脱保护基六步反应法可进行化学合成。
That is dehydrogenation and cyclization of paraffins, dehydrogenation and aromatization of naphthenes, and cracking reaction to form C 5 lighter products.
集总组分之间主要发生烷烃脱氢环化、环烷烃脱氢芳构化和加氢裂化反应。
METHODS Bretazenil was synthesized from 3-bromoaniline by cyclization, oxidation and ring-enlargement reaction, etc.
方法以3-溴苯胺为起始原料，经过成环、氧化、扩环等反应得到目标产物。
METHODS The compound was synthesized through the reaction of cyclization, split, bromination et al and using 1,3-propyl bromide and ethyl acetoacetate as raw materials.
方法以1，3-溴丙烷与乙酰乙酸乙酯为原料经环合、开环、溴代等反应合成。
METHODS The compound was synthesized through the reaction of cyclization, split, bromination et al and using 1,3-propyl bromide and ethyl acetoacetate as raw materials.
方法以1，3-溴丙烷与乙酰乙酸乙酯为原料经环合、开环、溴代等反应合成。
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