Since the virus can't gain a foothold on cells that lack CCR5, people who have the mutation have natural protection.

如果细胞上没有足够的CCR 5, HIV病毒就无法在细胞上立足，所以有发生这种突变的人自然可以受到保护。

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The mutation is known as CCR5 delta32 and is found in 1 percent to 3 percent of white populations of European descent.

这种CCR5 delta32的基因突变在欧洲的白人中的存在概率为1%到3%。

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HIV USES the CCR5 as a co-receptor (in addition to CD4 receptors) to latch on to and ultimately destroy immune system cells.

HIV利用CCR5为受体(除此之外还有CD 4型受体)来锁住并最终破坏免疫系统细胞。

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Other companies, including Pfizer and Schering-Plough, started developing drugs to target the gene, called CCR5.

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"Very senior management said I should stop working on integrase and start working on CCR5 inhibitors, " Hazuda says.

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But she insisted the right target was integrase, part of the virus, not CCR5, which is part of the patient.

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