The mutation is known as CCR5 delta32 and is found in 1 percent to 3 percent of white populations of European descent.
这种CCR5delta32的基因突变在欧洲的白人中的存在概率为1%到3%。
HIV USES the CCR5 as a co-receptor (in addition to CD4 receptors) to latch on to and ultimately destroy immune system cells.
HIV利用CCR5为受体(除此之外还有CD 4型受体)来锁住并最终破坏免疫系统细胞。
Before undergoing the transplant, the patient was also found to be infected with low levels of a type of HIV known as X4, which does not use the CCR5 receptor to infect cells.
在进行移植前，病人被发现感染了少量的一种HIV病毒，X4。这种病毒不利用CCR5作为受体来感染细胞。
CCR5 protein coverage in the major T-cell surface.
CCR5蛋白质主要覆盖于T细胞表面。
CCR5 protein coverage in the major T-cell surface, is a receptor protein.
CCR5蛋白质主要覆盖于T细胞表面，是一种蛋白受体。
CCR5, one of the coreceptors of HIV?1, is a new target of anti-HIV therapy.
趋化因子受体CCR5是HIV?1 进入靶细胞的辅助受体，因而成为开发抗艾滋病药物的新靶点。
As a result, and in the fight against AIDS, CCR5 has played a crucial role.
因此，在与艾滋病的斗争中，CCR5起到了极为关键的作用。
Other researchers are experimenting with gene therapy to fully prevent the emergence of CCR5.
其他研究人员正在试验基因疗法来完全阻止CCR5的产生。
Results Compared to B6 WT group, B6 CCR5 KO group succumbed to acute GVHD at an accelerated rate.
结果与B6WT组比较，B6CCR5KO组小鼠以更快的速度死于急性移植物抗宿主疾病（GVHD）；
Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). ?
目的研究细胞趋化因子受体5（CCR5）在乙型病毒性肝炎（HB）免疫发病机制中的作用。
The latter experiments also identified the cells on which CCR1 and CCR5 expression is important for promoting liver fibrosis.
最近的实验也表明表面有CCR1和CCR5表达的细胞在促进肝纤维化中也有重要作用。
Objective: to study the relation of RANTES and its receptor (CCR5) expression in gastric cancer and in lymph nodes with cancer metastasis.
目的：探讨RANTES及其受体(CCR5)在胃癌和转移淋巴结组织中的表达及其与胃癌转移的关系。
All of these biological effects are performed by binding of ligands to receptors. Elsewhere, CXCR3 and CCR5 are mark chemokine receptors in RA.
它们的这些生物学功能是通过配体与受体结合的方式来发挥的，而CXCR3与CCR5是RA中趋化因子的标志性受体。
Furthermore, expression of both CCR2 and CCR5 genes was enhanced significantly in activated macrophages when compared with non-activated macrophages.
而且，与 未激活的巨噬细胞比较，已经 激活的巨噬细胞CCR2，CCR5基因的表达增强更为明显。
CCR5, a membrane protein on cell surface, is a member of the G protein-coupled receptor superfamily and one of the major co-receptors for HIV-1infection.
CCR5为细胞膜蛋白，属于G蛋白偶联受体家族的成员，是HIV - 1入侵机体细胞的主要辅助受体之一。
Conclusion the expression of CCR5 is significantly correlated with the immune system reaction toward HIV and disease progression in HIV-1 infected patients.
结论HIV 1感染者第二受体ccr5的表达与机体对HIV的免疫反应及疾病进展密切相关。
Conclusion Expression levels of peripheral blood CD4 + t lymphocytes surface CCR5 may be closely related to the susceptibility to HIV infection and the disease progression.
结论此项研究表明外周血中CD 4 +T淋巴细胞表面CCR5表达的差异与HIV的易感性、疾病进展情况密切相关。
If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that ACTS as a kind of gateway.
假设将从父母遗传的基因突变称作Delta32，它通过阻断CCR5来阻止HIV附着于细胞上，CCR5是一种通道受体。
Histological assessment of the mice indicated pathological lesions in the kidneys and a greater degree of liver pathological changes in mice that received CCR5 KO donor grafts.
组织学评价提示，移植剔除CCR5基因受者细胞的小鼠肾脏出现了病理损伤并且肝脏存在有更为严重的病理变化。
"It helps prove the concept that if somehow you can block the expression of CCR5, maybe by gene therapy, you might be able to inhibit the ability of the virus to replicate," Fauci said.
Fauci说：“它帮助证明了一个概念，即如果基因治疗能阻断CCR5的表达，那就可能会抑制病毒的复制能力。”
Of that number, 36 had been previously identified. Those proteins include such long-known and well-studied proteins as the CD4 and CCR5 receptors that HIV uses to attach to a cell's surface.
在所发现的273个蛋白中，其中36个是过去已经确认了的，包括了认识和研究了很久的HIV在接近细胞表面所利用的蛋白CD4 和CCR5受体。
Determination of peripheral blood CD4 + t cell surface CCR5 expression levels may have certain important clinical significance in early diagnosis, treatment and prognosis of HIV infected patients.
外周血中CD 4 +T淋巴细胞表面CCR5表达的检测，将对HIV患者的早期诊断、治疗和判断预后具有一定的临床意义。
Determination of peripheral blood CD4 + t cell surface CCR5 expression levels may have certain important clinical significance in early diagnosis, treatment and prognosis of HIV infected patients.
外周血中CD 4 +T淋巴细胞表面CCR5表达的检测，将对HIV患者的早期诊断、治疗和判断预后具有一定的临床意义。
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