Dear Annie: I hope you and your readers have some suggestions for me, because I'm just about at the end of my rope.

亲爱的安妮：我希望您和您的读者可以给我提些建议，因为我实在是山穷水尽，毫无办法了。

youdao

I'm at the end of my rope.

我在我的绳索的末端。

youdao

I am at the end of my rope with this job.

我对我的工作实在是承不住了。

youdao

I lighted my lantern, and found that I was perched on a narrow ledge, almost at the end of my rope literally and figuratively.

VOA: special.2009.12.07

My partner, Tye, is clanking away in the darkness, unseen at the far end of the rope I'm holding.

WSJ: El Capitan's Nose in a Day | By Michael J. Ybarra