一、老年呼吸系统功能变 随年龄增长呼吸系统发生进行性老化现象--老人肺(aging Lung)。 1、肺通气功能明显减退,肺顺应性降低、气道阻力增加,呼吸储 备功能显著下降。
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Those genes with increased expression level in aging lung mainly related to cytoskeleton or extracellular matrix, inflammation or stress response, tumor, signal transduction and so on.
上调为主的有：细胞骨架和胞外基质、炎性应激反应、肿瘤相关、信号转导等；
Conclusions Aging could accelerate fibrin deposition in pulmonary tissue of LPS-induced rat model of acute lung injury, and promote the injury of endothelial cell function caused by fibrin deposition.
结论增龄能够促进脂多糖诱导的急性肺损伤大鼠肺组织纤维蛋白沉积，增强纤维蛋白的内皮细胞损伤作用。
Her study was supported by the National Institute on Aging, National Heart Lung and Blood Institute and National Institute of Arthritis and Musculoskeletal and Skin Diseases.
她的研究得到国家老龄研究所，国家心肺和血液研究所和国立关节炎及肌骨及皮肤疾病研究所的支持。
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