The subject is of no interest to me at all.

我对此课题一点也不感兴趣。

《牛津词典》

"I have tried, but it is of no use; I may just as well give up at once."

“我试过了，但是没有用；我还不如马上放弃。”

youdao

"It is of no use; I cannot learn." he said in a whisper to a companion who sat near him.

“这没有用；我学不会。”他低声对坐在他旁边的同伴说。

youdao

Harris Perlman says the best part of the new treatment is that there were no harmful or major side effects.

VOA: special.2010.03.16

So their national ties to the land in the north, in the south, the center is Jerusalem and its surroundings, Bethlehem is of no immediate interest to Islam.

所以他们与这片土地的联系,无论是北部，还是南部，都是国家层面的，中央的是耶路撒冷和周边，比如伯利恒，与伊斯兰教没有直接联系。

普林斯顿公开课 - 人性课程节选

The choice is a terrifying one of no friendship and "boughten friendship," which really isn't friendship at all.

这个选择是可怕的,是不要友谊还是根本不能算是友谊的“,“买来的友谊“

耶鲁公开课 - 现代诗歌课程节选

Those who argue that this region is of no strategic importance are simply wrong.

CENTERFORSECURITYPOLICY: Stop Serbia Now

Now what Amazon does in Luxembourg is of no matter to the UK taxman.

FORBES: Amazon's Outrageous Tax Dodging Ways

The existence of Harold Crick (Will Ferrell) is of no interest, even to Harold Crick.

NEWYORKER: Stranger Than Fiction