• 1. Secretase: 分泌酶 | 分泌素
• 2. gamma-secretase: 分泌酶
• 3. Beta-Secretase: 贝塔分泌脢 | 乙型分泌素

更多释义

• 1.Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
  当一种叫淀粉样前体蛋白（APP）的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
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• 2.For the past decade there has been a lot of work on drugs called secretase inhibitors, which alter the activity of the enzymes that create amyloid beta-peptide 42.
  在过去的10年里人们对被称为分泌酶抑制剂的药物进行了大量研究，这种药物可以改变酶类产生淀粉样贝塔-肽42的活动。
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• 3.Eberhart and colleagues studied glioblastoma cell lines to investigate the effects of a gamma-secretase inhibitor, a medication that blocks the Notch receptor, on tumor growth.
  埃伯哈特和他的同事们研究了恶性胶质瘤的细胞系以发现γ-内分泌酶抑制剂的影响，这种药物可阻断促使肿瘤增长的Notch受体途径。
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