凡·高对现代绘画的发展有着重大的影响。
Van Gogh had a major influence on the development of modern painting.
这次会演对我们城市乃至整个国家都将是意义重大的。
The festival will be great for our city and for the country as a whole.
信息科技已经对大型企业的生产力产生了重大的影响。
Information technology has had a significant impact on the productivity of large enterprises.
我们已经取得了重大的进展！
他那乐观的态度帮助他克服了一些重大的挑战。
His positive outlook helped him overcome some major challenges.
这是一项意义重大的决定。
今天让我做出所有的决定，重大的与微小的，真诚并富于勇气。
Today let me make all of my decisions, big and small, honestly and courageously.
在任何重大的“第一天”之前，记住父母一直对我们说的“做你自己！”
Before any big "first day," remember what our parents always told us, "Just be yourself!"
人生中，几乎每个重大的成功都是无数次的尝试后达到的——跌倒后站起来，再次尝试。
Almost every major accomplishment in a person's life starts with the decision to try again and again - to get up after every failed attempt and give it another shot.
我们最重大的责任之一就是保护我们的环境，因此我十分赞赏你们为此付出的努力。
One of the most vital responsibilities that we have is preserving our environment, and I applaud your efforts to do just this.
举办2010年上海世博会，对中国、对上海、对世博会事业都是一次重大的历史性机遇。
Hosting Expo 2010 Shanghai China is a historical opportunity for China, for Shanghai, and for the cause of World Exposition.
这是人生中一个重大的悖论：所有人都希望自己幸福，但似乎能真正知道幸福感源头的人却寥寥无几。
It's one of the great paradoxes of life that we all want to be happy, yet so few of us seem to know exactly where happiness comes from.
爱因斯坦的相对论是20世纪最为重大的理论变革之一，也可以说是人类思想的最伟大的理论构想。
Einstein's theory of relativity was one of the great revolutions of 20th-century thought, and arguably the greatest theoretical construct of the human mind.
体育运动仍然是希腊人生活的重要部分。希腊人通过奥运会对全世界的体育运动和体育精神产生了重大的影响。
Sports are still an important part of Greek life and, by giving us the Olympics, the Greeks have had a tremendous influence on world sports and sportsmanship.
因为我们知道气候变化是我们当今时代所面临的重大的道德、经济和环境挑战，是所有国家必须携手合作、共同克服的困难。
Because we know that climate change is the great moral, economic and environmental challenge of our time -one that all nations have to work together to overcome.
一旦消灭脊髓灰质炎，世界人民就可以庆祝完成了一项重大的全球公益事业——所有人，不论其生活在何处，都将能平等地从中获益。
Once polio is eradicated, the world can celebrate the delivery of a major global public good - something that will equally benefit all people, no matter where they live.
一旦消灭了脊髓灰质炎，世界人民就可以庆祝完成了一项重大的全球公益事业，所有人，而不论其生活在何处，都将能平等地从中获益。
Once polio is eradicated, the world can celebrate the delivery of a major global public good that will benefit all people equally, no matter where they live.
对于那些艺术、戏剧与电影专业的学生来说，毕业是一个重大的节日。在全国的各所高校里，毕业生们正在展示着自己最好的作品。
For students majoring in art, theater and film, graduation is a festival event: They are showcasing their best work on campuses all over the country.
妇幼保健是我们亟需看到取得重大进展的另一个领域。
Another area where we urgently need to see significant progress is on women's and children's health.
一个国际保护组织称，拯救稀有沙漠动物阿拉伯大羚羊的努力取得了重大成功。
An international conservation group says efforts to save a rare desert animal known as the Arabian oryx have been a major success.
只有以这种方式欣然接受并利用你的错误，你才能在业务和事业上取得重大进步。
Only by embracing and using your mistakes in this way can you make significant advances in your business and your career.
过去20年的数据显示，许多国家在预防和治疗视力损害方面取得了重大进展。
Data over the last 20 years shows that there has been significant progress in preventing and curing visual impairment in many countries.
一项重大研究警告称，10岁的孩子开始依赖社交媒体来获得自我价值感。
Children as young as ten are becoming dependent on social media for their sense of self-worth, a major study warned.
1941年去世的美国语言学家本杰明·李·沃尔夫认为，每种语言都蕴含着一种世界观，这种世界观会对使用者产生重大影响。
Benjamin Lee Whorf, an American linguist who died in 1941, held that each language encodes a worldview that significantly influences its speakers.
相互尊重对方的重大关切和核心利益，坚持通过对话协商解决分歧。
We should respect each other's major concerns and core interests and resolve differences through dialogue and consultation.
我们正处于一场重大变革的风口浪尖。
我知道在面对重大挑战和困难的时刻，我们并不惧怕未来——我们能塑造未来。
I know that in times of great challenge and difficulty, we don't fear the future - we shape the future.
我知道在面对重大挑战和困难的时刻，我们并不惧怕未来——我们能塑造未来。
I know that in times of great challenge and difficulty, we don't fear the future - we shape the future.
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