我们计划向慈善机构捐款，希望它给人们带来重大的影响。
We are planning to donate money to a charity and want it to have a major impact on people.
房屋已经倒塌，但我们可以重建它们。只要人活着，我们就一定能够渡过难关，并战胜这场重大的自然灾害。
Houses have been split and collapsed, but we can build them again. So long as people are alive, we can still pull through and conquer the major natural disaster.
那些拥有强有力的支持系统的人似乎能够更好地应对重大的生活变化和日常困难。
Those of us with strong support systems appear better able to cope with major life changes and daily hassles.
每一项重大的科学发现都是从发明者以一种独特的视角来看待问题开始的。
Every major scientific discovery began with someone imagining the world to look differently from the way others saw it.
他的同事、托莱多大学的地质学家詹姆斯·哈雷尔说：“这条路可能不算是一项与金字塔相媲美的建筑壮举，但却是一项重大的工程成就。”
"The road probably doesn't rank with the pyramids as a construction feat, but it is a major engineering achievement," said his colleague, geologist James Harrell of the University of Toledo.
每个考古学家的梦想都是找到一个失落的文明，做出一些重大的发现，找到千年来无人触及的手工艺品。
It's every archaeologist's dream to find a lost civilization, to make some huge discovery, to find artifacts no one else has laid a hand on in millennia.
英吉利海峡隧道对于建立一个统一的欧洲具有重大的象征意义。
The Channel Tunnel has enormous symbolic significance for a united Europe.
从好的方面来说，它可以重现你人生中最重大的转折和最丰富多彩的经历。
On the plus side, it allows you to relive the most transformative and enriching experiences.
新的事件区在外观和功能上都做了重大的更新。
The new Events section is a major upgrade from the previous version, both in appearance and functionality.
他那乐观的态度帮助他克服了一些重大的挑战。
His positive outlook helped him overcome some major challenges.
比起过去二十年做过的实验来说，这是个重大的进展。
This is a significant advance compared to experiments that have been performed over the past 20 years.
这对风能、太阳能、核能和生物能来说，是重大的促进因素。
These are significant positives for alternative energies such as wind, solar, nuclear, and bio-fuel.
斯诺·马斯化石遗址是科罗拉多州历史上最重大的发现之一。
The fossil site in Snowmass is one of the most significant discoveries in Colorado history.
在最好的情况里，父母可以协助你做重大的决定并支持你的选择。
In the best of situations, parents can help you make important decisions and support your choices.
然而一旦大型粒子对撞机完全运行，它将给物理学带来重大的变革。
Once it is running properly, though, it is expected to bring about a fundamental rethinking of physics.
这次胜利对希腊而言意义非凡，因为他们从来不曾在重大的锦标赛中获胜。
Their victory was particularly meaningful because Greece had never won a game at a major tournament before.
云计算技术又称“空中硬盘”，它将使我们的工作和生活发生重大的转变。
Cloud computing, aka the "hard drive in the sky," is going to cause yet another major shift in the way we work and live.
这是一个重大的战略性论断，希望在两国国内得到广泛支持，不断深入人心。
This is a major strategic judgment which I hope, will find wide and deep support in both countries.
一位科学家近期预言，未来最重大的成果将产自在大量归档数据中发现模式。
One scientist recently predicted that the great discoveries of the future will come from finding patterns in vast archives of data.
今年我在工作上做了一些重大的决定，并且被一所很好的大学录取了。
This year I did make some big decisions about my career and got accepted into a great school.
将移动钱包业务扩展到其它尤其是非洲和亚洲贫穷国家会产生重大的影响。
Extending mobile money to other poor countries, particularly in Africa and Asia, would have a huge impact.
人生中，几乎每个重大的成功都是无数次的尝试后达到的——跌倒后站起来，再次尝试。
Almost every major accomplishment in a person's life starts with the decision to try again and again - to get up after every failed attempt and give it another shot.
这个重大的突破允许直接检测每个核苷酸，可以在大约一小时之内测序整个基因。
The breakthrough permits direct detection of each nucleotide, allowing an entire gene to be sequenced in about an hour.
当我在这里继续写作那篇小说和《晚歌集》的时候，一个重大的变革在我心里发生。
While I went on here with the novel and the Evening Songs, a momentous revolution of some kind came about within me.
我们最重大的责任之一就是保护我们的环境，因此我十分赞赏你们为此付出的努力。
One of the most vital responsibilities that we have is preserving our environment, and I applaud your efforts to do just this.
举办2010年上海世博会，对中国、对上海、对世博会事业都是一次重大的历史性机遇。
Hosting Expo 2010 Shanghai China is a historical opportunity for China, for Shanghai, and for the cause of World Exposition.
这是人生中一个重大的悖论：所有人都希望自己幸福，但似乎能真正知道幸福感源头的人却寥寥无几。
It's one of the great paradoxes of life that we all want to be happy, yet so few of us seem to know exactly where happiness comes from.
爱因斯坦的相对论是20世纪最为重大的理论变革之一，也可以说是人类思想的最伟大的理论构想。
Einstein's theory of relativity was one of the great revolutions of 20th-century thought, and arguably the greatest theoretical construct of the human mind.
爱因斯坦的相对论是20世纪最为重大的理论变革之一，也可以说是人类思想的最伟大的理论构想。
Einstein's theory of relativity was one of the great revolutions of 20th-century thought, and arguably the greatest theoretical construct of the human mind.
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