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    Constitutive activation of the pathway involving these two genes appears to be a major contributor to the development of uveal melanoma. (Funded by the National Institutes of Health and others. ).

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    JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.

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  • JAK2一种组成性酪氨酸激酶激活JAK - STAT信号传导途径

    JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.

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