为了进一步提高外源蛋白质的分泌表达，对信号肽序列进行了研究。
For further improving the secretion expression of heterogeneous proteins, in this research, the signal sequences were studied.
将胰岛素原基因融合到金色葡萄球菌蛋白a的基因上，构建成大肠杆菌中基因融合的外分泌表达载体。
The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.
结论构建了人瘦素的哺乳动物细胞表达载体，并成功地在COS 7细胞中获得重组人瘦素的分泌表达。
Conclusion Cloning and expression recombinants of human leptin are obtained and secretive recombinant human leptin is successfully expressed in COS-7 cells.
阿托伐他汀可通过脂肪组织及内皮细胞抑制炎症介质的分泌及表达。
Atorvastatin can suppress the expression and release of inflammatory mediator by adipose tissue and endothelial cells.
电针可以增加大鼠脑缺血区皮层ngf的分泌和表达时程，这可能是其保护缺血性脑损伤的机制之一。
Ea can increase the secretion and expression period of NGF in rats ischemic cortex, and this may be one of its protective mechanisms for ischemic cerebral damage.
通常，人体分泌激素是为了调节各项生理机能，它们就像乐队指挥官，调控着基因表达的开启或终止。
Typically, the human body in order to regulate secretion of hormones are the physiological functions, they like the band commander, regulation of gene expression in open or terminated.
研究表明，组蛋白的乙酰化与去乙酰化状态，可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。
Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.
紫外线作用于成纤维细胞，引起细胞因子分泌及基因表达的改变，不仅能造成真皮层的损伤，还可被用来治疗某些疾病，如局限性硬皮病。
Ultraviolet not only causes dermal damages by changing cytokine secretion and gene expression of human skin fibroblasts, but also is used to treat some diseases such as localized scleroderma.
结论：GLP鄄1可促进大鼠胰岛细胞胰岛素基因的表达和蛋白的分泌，对大鼠胰岛细胞亦有明显的促增殖作用。
Conclusion: GLP-1 can not only increase the insulin gene expression and insulin secretion, but also stimulate the proliferation of islet cells.
这种靶向性的策略包括目的基因对肿瘤细胞的靶向转移，目的基因在肿瘤细胞中的特异表达，以及基因修饰细胞分泌的肿瘤靶向治疗分子。
This can be achieved by tumor targeted gene transfer or tumor specific gene expression, as well as secretion of tumor targeted therapeutic molecules by autologous normal cells.
瘤周正常垂体组织和垂体腺瘤组织中与垂体激素分泌及能量代谢有关的一些基因表达水平较高。
The genes related to pituitary hormone secretion and energy metabolism were highly expressed in the two kinds of tissues.
生长抑素（SS）通过抑制垂体生长激素的分泌而影响机体的生长性能，SS同时也能抑制钙蛋白酶的表达和活性。
Somatostatin (SS) is the major inhibitory factor for growth hormone secretion and has also been reported to attenuate the expression and activity of calpains.
醛固酮合酶(CYP11B2)是醛固酮生物合成最后一步的催化酶。醛固酮的分泌主要由醛固酮合酶的表达水平来调节。
Aldosterone secretion is regulated largely at the level of expression of the final enzyme required for its biosynthesis, aldosterone synthase (CYP11B2).
肿瘤细胞高表达生长因子和神经节苷脂，并将生长因子分泌到或将神经节苷脂脱落于肿瘤细胞周围的微环境中。
Growth factors and gangliosides are highly expressed in tumor cells, and secreted and shedded into the microenvironment of tumor cells respectively.
已知的AR-V7变异体也在一组筛选后患者群中高表达，这群患者从未经历内分泌治疗，但其肿瘤在手术切除后复发性强。
One variation - known as AR-V7, was also prevalent in a select group of patients who had never taken hormone therapy, but whose cancer aggressively regrew after surgery to remove their tumors.
这个动作会让它的面部腺体分泌油脂，它在用自己特有的方式在表达：主人你是我的。
This act secretes oils from her facial glands. It's her way of claiming you as her own.
阿托伐他汀可抑制炎症介质的分泌及表达，具有抗炎作用。
Atrovastatin suppress expression of inflammatory mediator. It has an effect of anti-inflammation.
了解不同发育、生长时期和不同生理、病理条件下及不同类型细胞分泌蛋白表达的特点对认识生命过程具有重要意义。
The understanding of the secretory protein expression characteristics of different growth period and different physiological or pathological conditions is of great significance.
目的：探讨富含半胱氨酸的分泌型酸性蛋白(SPARC)在宫颈癌中的表达变化及其与宫颈癌生物学行为的关系。
Objective: To investigate the expression of secreted protein acidic and rich in cysteine (SPARC) in cervical carcinoma and its relationship with biological behavior of cervical carcinoma.
目的探讨在大鼠胰腺移植急性排斥反应中调节激活正常T细胞表达和分泌因子(RANTES)的作用。
Objective To investigate the role of regulated upon activation, normal t cell expressed and secreted (RANTES) in the acute pancreatic allograft rejection in rats.
有研究证明调节活化正常T细胞表达和分泌因子（RANTES）与类风湿关节炎、干燥综合征等多种自身免疫疾病相关。
Researches have demonstrated that Regulated on Activation, Normal T cell Expressed and Secreted ( RANTES) was related to autoimmune disease, such as Rheumatoid Arthritis and Sjogren Syndrome.
结论：氯化镧能够抑制肿瘤细胞生长，并抑制细胞MMP - 2的表达和分泌，为进一步开发抗肿瘤药物提供了参考。
CONCLUSION Collectively, these results suggest that lanthanide chloride is a potent drug for inhibition of MMP-2 expression in carcinoma cells.
目的探讨高脂饮食对大鼠神经肽Y（NPY）基因表达及分泌的影响及大鼠肥胖易感性差异的机制。
Objective To explore the effect of high-fat diet on the hypothalamic neuropeptide Y(NPY)expression and the mechanisms which predispose some individuals to become obese on high-fat diet.
结果芯片结果显示实验组已知功能差异表达基因有16条。其中下调基因有13条，4条与内分泌调控密切相关。
Results 16 identified genes expressed differently, including 13 down-regulated in which 4 were related to endocrine regulation.
部分胰岛细胞、胰腺外分泌细胞和所有导管上皮细胞均表达人类血型A抗原。
The human blood a type antigen was highly expressed on some islet cells, some exocrine secretory cells and all the duct epithelium.
本文对CD 57免疫反应性在人胰腺内分泌细胞中表达的意义进行了讨论。
The significance of the expression of CD57 immunoreactivity in endocrine cells of human pancreas was discussed.
解读材料指出，内分泌腺体是身体的精神中心，我们的精神力量通过它们得以表达。
They suggest that the endocrine glands are the spiritual centers of the body and that through them our spiritual forces find means of expression.
高浓度的葡萄糖、糖皮质激素、脂肪酸可抑制PDX-1蛋白的表达，从而抑制胰岛细胞的胰岛素分泌功能。
Exposure of islet cells to high concentration of glucose, dexamethosone and palmitate can reduce the expression of PDX-1, therefore affects the insulin synthesis of islet cells.
在胰的外分泌部和内分泌部（胰岛）均可观察到生长素的表达。
Ghrelin immunopositive cells were simlarly observed in the exocrine portion and endocrine portion (pancreas islet) of pancreas.
在胰的外分泌部和内分泌部（胰岛）均可观察到生长素的表达。
Ghrelin immunopositive cells were simlarly observed in the exocrine portion and endocrine portion (pancreas islet) of pancreas.
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