与附近目标酶的活性位点不可逆的结合。
Blocks the action of target enzymes by binding nearly irreversibly to their active site.
另一个例证是，葛兰素史克公司的研究人员最近描述了一种以iia型拓扑异构酶为作用目标的新的抗菌剂。
Another example is that of researchers at GlaxoSmithKline who recently described a novel class of antibacterial agents that target type IIA topoisomerases.
研究人员说，尽管这项技术可以被应用于多种蛋白质的检测，他们目前的首要目标是凝血酶。
Researchers say the technology could be adapted to detect a number of different proteins, but they are focusing first on thrombin.
在经过此次研究后，我们能够掌握如何生产出这种保护性的抗体酶，而未来的目标则是将其生产为可预防艾滋病毒的疫苗，从源头遏制这种可怕的病毒的传播。
We have learned a lot from this research about how to induce the production of the protective abzymes on demand. This is the Holy Grail of HIV research -- development of a preventative HIV vaccine.
而且多次从酶家族P38激酶中寻求新目标的尝试也失败了，尽管动物试验的结果比较积极。
And several attempts to carve a new target from a family of enzymes called p38 kinases have also failed, despite favourable results in animal models.
由于它在大量人类肿瘤中都过于活跃，这意味着该生物酶是未来药品的目标。
That meant the enzyme was a potential drug target, since it has been found to be overactive in the vast majority of human tumors.
充分阐明这些酶和它们管理的蛋白分子间复杂的相互作用已成为科学家们了解基因调控机制的首要目标。
Fully explicating the complex interplay among these enzymes and the molecules they manage has been a primary goal for scientists seeking to understand the mechanisms governing gene control.
在这个实施方案中，底物为蛋白水解酶提供裂解目标。
In this embodiment, the substrate provides a cleavage target for a proteolytic enzyme.
但肿瘤酶的具体目标蛋白质，并将其删除。
But the tumour enzyme specifically targets the protein and removes it.
以功能性大豆多肽饮料的研制为目标，探讨了以豆饼为原料酶解制备大豆多肽过程中的酶解条件。
The condition of enzyme decomposition was discussed during prepare polypeptide with bean cake in order to manufacture polypeptide drink used functionality soybean.
肉碱软脂酰转移酶作为治疗糖尿病的潜在目标：抑制还是激活，哪个更好？
Carnitine palmitoyltransferase as a potential target for treating diabetes: Is inhibition or activation preferable?
在心肌细胞的功能方面，泛素连接酶的生物学性能将被总结概括，并且，其作用将会被看作为潜在的治疗目标。
The biology of ubiquitin ligases in the context of cardiomyocyte function will be summarized, and the roles for these ubiquitin ligases will be discussed as potential therapeutic targets.
在心肌细胞的功能方面，泛素连接酶的生物学性能将被总结概括，并且，其作用将会被看作为潜在的治疗目标。
The biology of ubiquitin ligases in the context of cardiomyocyte function will be summarized, and the roles for these ubiquitin ligases will be discussed as potential therapeutic targets.
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