If the fusion protein of VP1 and VP2 that was expressed in E. coli can form neutralizing antigen epitopes, this problem is resolved.
如果大肠杆菌中表达的VP1和VP2融合蛋白也能形成中和抗原表位，则解决了这个问题。
Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice.
目的构建柯萨奇病毒（CV）B1/B3型二价VP1基因免疫质粒，并探讨其免疫原性。
And identified HEV71 isolates were performed by gene amplification of VP1 coding region, nucleotide sequencing and homology analysis of evolution.
对分离到的HEV71阳性分离株进行VP1编码区基因扩增，核苷酸序列测定和同源进化分析。
VP1-2A nucleotide fragments from 5 samples were cloned and sequenced. The results showed that VP1-2A nucleotide fragments of 5 strains were identical.
选择5份标本进行VP1 - 2a基因片段序列测定，测序结果经过比对后发现，5株的VP1 - 2 A序列完全一致。
VP1-2A nucleotide fragments from 5 samples were cloned and sequenced. The results showed that VP1-2A nucleotide fragments of 5 strains were identical.
选择5份标本进行VP1 - 2a基因片段序列测定，测序结果经过比对后发现，5株的VP1 - 2 A序列完全一致。
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