Conclusion Nucleotide sequence in VP1 region is correlated with enterovirus serotype.

结论V P 1区核苷酸序列同病毒血清型相关联。

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If the fusion protein of VP1 and VP2 that was expressed in E. coli can form neutralizing antigen epitopes, this problem is resolved.

如果大肠杆菌中表达的VP1和VP2融合蛋白也能形成中和抗原表位，则解决了这个问题。

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Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice.

目的构建柯萨奇病毒（CV）B1/B3型二价VP1基因免疫质粒，并探讨其免疫原性。

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