The creation of the message that represents the request and response and the transfer of this data across the network create substantial overhead.
创建表示请求和响应的消息，并跨网络传输这些数据会产生巨大的开销。
The global response to the 2009 pandemic has provided a substantial amount of new experience and evidence in public health responses to influenza, its treatment and prevention.
2009年大流行的全球应对为流感的公共卫生应对、治疗和预防提供了大量新的经验和证据。
For repository interactions, where the number of rows in the database will differ greatly between 10,000 resources and 100,000 resources, there is a substantial increase in the response time.
对于存储库的交流，数据库中行的数量，在10,000个资源与100,000个资源之间发生显著的波动，在响应时间上会发生很大的波动。
Strain response of the engine block is gained at some primary points by dynamic real time test under substantial load. Meanwhile result of calculation is verified by the test.
通过机体的动态实时测试，获得了机体所受真实载荷下主要点的应变响应，并通过试验对计算结果进行了验证。
Despite a substantial biologic response, the administration of basic fibroblast growth factor failed to produce improvements in either the mechanical or functional properties of the repair.
尽管有大量的生物学反应，但是屈肌腱修复后应用碱性成纤维细胞生长因子既不能提高肌腱的机械性能也不能促进其功能特性。
With substantial oil recovery equipments, Offshore Contingency Response Center of Shengli Oilfield was founded in July, 1997.
胜利油田于97年7月成立了海洋应急中心，配备了相应规模的溢油回收设备。
Phosphorylation of PP2A at Tyr307 by Src occurs in response to EGF or insulin and results in a substantial reduction of PP2A activity (4).
Src介导的PP2A第307位酪氨酸磷酸化响应EGF或者胰岛素，最终导致PP2A的活性显著下降（4）。
Now in response I must ask, ultimately what substantial practice can stop the planet from getting warmer, and can reduce environmental pollution?
那我倒要请教，到底有什么实质性的做法可以减少地球变暖，可以减少环境污染？我希望能得到实质性的答案。
In addition, the ATR Ratchet will often add substantial additional acceleration in response to increases in volatility during the trade.
此外，波动性增加也会提高ATR棘轮止损点上移的速度。
In addition, the ATR Ratchet will often add substantial additional acceleration in response to increases in volatility during the trade.
此外，波动性增加也会提高ATR棘轮止损点上移的速度。
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