In all those samples, there were no alterations in the subcellular distribution of cytochrome oxidase, a mitochondrial respiratory chain protein.
在所有样品中，线粒体呼吸链蛋白细胞色素氧化酶没有变化， 表明线粒体的制备方法是可靠的。
Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.
结论DNR在耐药细胞中的异常分布与肿瘤细胞耐药基因形成有关，槲皮素在体外直接抑制MRP1功能，恢复DNR在细胞内的分布。
Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.
结论DNR在耐药细胞中的异常分布与肿瘤细胞耐药基因形成有关，槲皮素在体外直接抑制MRP1功能，恢复DNR在细胞内的分布。
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