This isn't the first time researchers have looked at PTEN.
这并不是研究者们第一次关注PTEN。
Extrons of PTEN gene were detected by PCR in all of 8 cases.
在所分析的8例骨巨细胞瘤中，PCR均检测到PTEN基因的外显子。
Furthermore, the inactivation of PTEN is associated with occurrence of tumor.
PTEN的失活与肿瘤的发生紧密联系。
Mutations in the mitochondrial PTEN-induced kinase 1 cause early onset recessive Parkinson's.
线粒体中pten引起的激酶1的突变会引起早发型阿尔茨海默病。
AIM: to investigate the expression of PTEN protein in retinoblastoma and its clinical significance.
目的：探讨pten蛋白在视网膜母细胞瘤组织中的表达及临床意义。
Therefore, H2O2 is consider to participate in PTEN signal transduction as a intracellular messenger.
因此可认为H2O2作为细胞内信使，参与pten信号转导。
Objective: To study the relationship of expression of CDX2 and PTEN proteins and gastric metaplasia .
目的：探讨CDX2和PTEN蛋白表达与胃黏膜肠上皮化生的关系。
Objective To explore the expression and clinical significance of PTEN gene in large intestine carcinoma.
目的探讨抑癌基因pten蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN and DPC4 gene in large intestine carcinoma.
目的探讨抑癌基因DPC4和PTEN蛋白在大肠癌的表达及临床意义。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
Objective: To study the expression and significance of PTEN in normal salivary gland and salivary gland carcinoma.
目的：研究pten在正常涎腺组织及涎腺癌中的表达及意义。
If there's more of the enzyme, the PTEN gene seems to do a shoddier job of keeping an eye on keeping cancer at bay.
如果有更多这种酶的话，PTEN基因将像一位战士一样密切注意防止癌症。
Objective: To study the relationship between PTEN expression and HCV core protein in hepatocellular carcinoma (HCC).
目的：研究抑癌基因PTEN在人肝细胞肝癌中的表达及其与HCV核心蛋白间的关系。
Objective To investigate the expression and significance of tumor suppressor gene protein PTEN in malignant melanoma.
目的探讨pten基因蛋白在恶性黑素瘤中的表达及其意义。
The positive rates of PTEN in invasive cancer were lower than noninvasive breast cancer and the control group(P<0.01).
浸润性乳腺癌中PTEN的表达低于非浸润性乳腺癌及非肿瘤病变组织对照组（P<0.01）。
Conclusion Depletion of expression PTEN protein hints high malignancy degree of esophageal carcinoma and poor prognosis.
结论PTEN蛋白的表达缺失提示食管癌恶性程度较高，预后较差。
In most cases, the protein that PTEN produces was undetectable in tumor cells, but clearly present in nearby normal cells.
在大多数的病例的肿瘤细胞中都检测不到PTEN产生的蛋白，但这种蛋白存在于周围的正常组织中。
Then, study on the expression and regulation of PTEN in gliomas will help to further understand the function of PTEN in glioma.
因此进一步明确PTEN基因在胶质瘤中的表达与调控机制，有助于我们深入了解PTEN在胶质瘤发生中的作用。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
Combination of PTEN , VEGF and PCNA detection may be helpful to evaluate prognosis and infiltrative capability of gastric carcinoma.
联合检测PTEN、VEGF和PCNA，有助于提高胃癌侵袭转移能力的评估，对胃癌的预后判断具有重要的临床意义。
Emerging therapies that rely on the immune system to fight cancer could potentially be more or less effective based on PTEN function.
基于PTEN功能，目前时兴的依赖于免疫系统抗肿瘤的治疗方法可能更有效果或效果较差。
Objective to construct and express a recombinant adenovirus vector which can regulate expression of human tumor suppressor gene PTEN.
目的体外构建和表达可调控性人抑癌基因pten重组腺病毒。
Normal expression of PTEN may play an important role in suppressing focal adhesion formation, spreading and migration of melanoma cells.
推测pten基因的正常表达在抑制脉络膜黑色素瘤细胞的聚集黏附过程中具有重要作用。
At the same time, PTEN has the high homology with tensin and auxilin, PTEN may suppress cell migration, spreading, and adhesion formation.
同时PTEN氨基酸序列与张力蛋白和辅助蛋白高度同源，对细胞迁移、扩展、局灶黏附活动有抑制作用。
Conclusion Overexpression of PTEN will induce G1 arrest in rar renal fibroblast cells, which associated with the nuclear location of PTEN.
结论PTEN过度表达将引起肾脏成纤维细胞周期G 1期阻滞，这一过程与PTEN在细胞核定位有关。
The researchers found that inactivating the PTEN gene in mice led to the formation of the malignant tumor associated with BRCA1 mutations.
研究者们发现具有PTEN基因活性降低的小鼠会导致与BRCA1突变有关联的恶性肿瘤的形成。
More recently, it has been found that PTEN is closely related to cell size, especially to neuron enlargement and cardiomyocyte hypertrophy.
但近来有研究表明，PTEN与细胞的体积大小有密切关系，尤其是神经元和心肌细胞肥大。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因，可以负性调节肿瘤细胞的生长。
Methods the expression of AKT, PTEN had be detected for the specimens of 48 osteosarcoma and 15 exostosis with immunohistochemistry SABC method.
方法采用免疫组织化学SABC法检测48例骨肉瘤、15例骨软骨瘤标本中akt、PTEN表达的阳性细胞。
Conclusion: the exogenous PTEN gene may induce denaturalization, necrosis, and apoptosis of the highly metastatic mucoepidermoid carcinoma cells.
结论：外源野生型PTEN基因的转染能导致体外培养的高转移性黏液表皮样癌细胞变性、坏死或凋亡。
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