Previous work has shown that miR-17 ~ 92 can be involved in the survival of lymphoma and leukemia cells by reducing the levels of a tumor-suppressing protein called PTEN.
以前的工作已证实，miR - 17 ~ 92能通过降低肿瘤抑制蛋白pten的水平而促进淋巴瘤和白血病生长和存活。
The team's new research shows that miR-17 ~ 92 can also be involved in retinoblastoma, although it does not act in the same way, via the PTEN protein, as it does in other types of cancers.
这个团队的新研究显示，miR - 17 ~ 92还能够促进成视网膜细胞瘤的生长，不过这次并非通过PTEN蛋白发挥作用。
PTEN is like the brakes, he said.
PTEN基因像刹车一样，他还说。
PTEN Level in Tumor Suppression: How Much Is Too Little?
肿瘤抑制中pten基因的水平：多少是过少？
This isn't the first time researchers have looked at PTEN.
这并不是研究者们第一次关注PTEN。
Extrons of PTEN gene were detected by PCR in all of 8 cases.
在所分析的8例骨巨细胞瘤中，PCR均检测到PTEN基因的外显子。
Furthermore, the inactivation of PTEN is associated with occurrence of tumor.
PTEN的失活与肿瘤的发生紧密联系。
Detection of PTEN might be useful for judgement of tumor development and prognosis.
PTEN表达的检测有助于肿瘤的诊断和判断其预后。
PTEN (138G6) Rabbit mAb (Biotinylated) detects endogenous levels of total PTEN protein.
兔单抗可以检测内源性的总PTEN蛋白。
AIM: to investigate the expression of PTEN protein in retinoblastoma and its clinical significance.
目的：探讨pten蛋白在视网膜母细胞瘤组织中的表达及临床意义。
PTEN protein; extracellular signal-regulated kinase; squamous cell carcinoma; immunohistochemistry.
PTEN蛋白；细胞外信号调节激酶；鳞状细胞癌；免疫组化。
The PTEN knock-out mouse is one model of chronic liver injury that ultimately leads to liver cancer.
PTEN基因敲除的小鼠是一种慢性肝损伤模型，最终导致肝癌。
Objective To study the expression of PTEN and its clinicopathological significance in breast cancer.
目的：研究抑癌基因pten在乳腺癌中的表达并探讨其临床意义。
Objective: To study the relationship of expression of CDX2 and PTEN proteins and gastric metaplasia .
目的：探讨CDX2和PTEN蛋白表达与胃黏膜肠上皮化生的关系。
Objective To study the effect of PTEN on airway inflammation in a rat bronchial asthma (asthma) model.
目的探讨pten在支气管哮喘(简称哮喘)大鼠气道炎症中的作用。
Objective To investigate the new progresses in tumor suppressor gene PTEN and esophageal carcinoma(EC).
目的了解抑癌基因PTEN在食管癌（ EC）中的最新研究进展。
Objective To explore the expression and clinical significance of PTEN gene in large intestine carcinoma.
目的探讨抑癌基因pten蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN and DPC4 gene in large intestine carcinoma.
目的探讨抑癌基因DPC4和PTEN蛋白在大肠癌的表达及临床意义。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
Objective: To study the expression and significance of PTEN in normal salivary gland and salivary gland carcinoma.
目的：研究pten在正常涎腺组织及涎腺癌中的表达及意义。
Objective: To study the relationship between PTEN expression and HCV core protein in hepatocellular carcinoma (HCC).
目的：研究抑癌基因PTEN在人肝细胞肝癌中的表达及其与HCV核心蛋白间的关系。
Objective To investigate the expression and significance of tumor suppressor gene protein PTEN in malignant melanoma.
目的探讨pten基因蛋白在恶性黑素瘤中的表达及其意义。
The positive rates of PTEN in invasive cancer were lower than noninvasive breast cancer and the control group(P<0.01).
浸润性乳腺癌中PTEN的表达低于非浸润性乳腺癌及非肿瘤病变组织对照组（P<0.01）。
Conclusion Depletion of expression PTEN protein hints high malignancy degree of esophageal carcinoma and poor prognosis.
结论PTEN蛋白的表达缺失提示食管癌恶性程度较高，预后较差。
Mice with CARN cells lacking PTEN quickly developed carcinomas, whereas mice with functional PTEN in CARN cells did not.
PTEN基因缺失的CARN细胞的小鼠很快就产生肿瘤，同时，有功能的PTEN基因的CARN细胞的小鼠则不产生肿瘤。
In most cases, the protein that PTEN produces was undetectable in tumor cells, but clearly present in nearby normal cells.
在大多数的病例的肿瘤细胞中都检测不到PTEN产生的蛋白，但这种蛋白存在于周围的正常组织中。
To study the relationships between the expression level of PTEN gene, gene mutation and occurrence and development of glioma.
目的：探讨pten基因表达水平及其基因突变与脑胶质瘤的发生及恶性进展的关联性。
The PTEN protein expression deletion rates in BTCC were significantly associated with histological grades and clinical stages.
PTEN的表达随病理分级、临床分期的增高而明显下降。
Then, study on the expression and regulation of PTEN in gliomas will help to further understand the function of PTEN in glioma.
因此进一步明确PTEN基因在胶质瘤中的表达与调控机制，有助于我们深入了解PTEN在胶质瘤发生中的作用。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
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