Protein splicing not only enriches genetic theory of posttranslational processing, but also have wide application prospect.
蛋白质内含肽的发现,不仅丰富了遗传信息翻译后加工的理论,在实践中也有广泛的应用前景。
Some recent advance in the study of the structure and function of the intein as well as the mechanism of intein-mediated protein splicing and its application are described in this review.
介绍了蛋白质内含子的结构、功能和其介导的蛋白质剪接机理及应用研究进展。
By splicing the Bt gene that manufactures its toxic protein into the plant (say, corn or potatoes), the entire plant is rendered toxic to the pest, all without the use of pesticides.
通过接合Bt产毒素的基因入植株上,那么整棵植物都可以抵御昆虫而不需农药了。
K protein contains multiple modules that, on one hand, bind kinases while, on the other hand, recruit chromatin, transcription, splicing and translation factors.
蛋白包含多种分子,不但可以结合激酶,还能募集染色质、转录、剪切和翻译因子。
This will help us to investigate controllable protein cleavage in vitro, further establish efficient protein purification system and investigate splicing mechanism of split-inteins.
这将为进一步研究其体外可控性剪接、构建高效的蛋白纯化系统和深入研究蛋白质内含子的剪接机制提供基础。
Histone marks affect splicing outcome by influencing the recruitment of splicing regulators via a chromatin-binding protein.
组蛋白标记经由一个染色质结合蛋白质,通过影响剪接调控子的招募而影响剪接结果。
Intronic mutations may affect gene regulation through aberrant splicing or disruption of critical DNA protein interactions.
内含子突变可以通过引起剪接异常或关键性DNA -蛋白反应中断而影响基因调控。
Until 20 years ago, scientists believed that a single gene made a single protein. With the discovery of alternative splicing, it became clear that one gene can produce multiple proteins.
20年前,科学家们都认为一个基因对应一个蛋白,当发现选择性剪切后就知道了一个基因可以生成多种不同的蛋白。
Until 20 years ago, scientists believed that a single gene made a single protein. With the discovery of alternative splicing, it became clear that one gene can produce multiple proteins.
20年前,科学家们都认为一个基因对应一个蛋白,当发现选择性剪切后就知道了一个基因可以生成多种不同的蛋白。
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