But it's not yet known whether the variant protects against other prion diseases.
但是目前还不清楚这一变异是否对其他由朊病毒引起的疾病有效。
The molecular changes did not, though, seem to change the aminothiazoles' prion-killing attributes.
氨噻唑分子的改变似乎并没有改变其杀灭朊病毒的特性。
Together with his colleagues, he studied four different strains of mice lacking the gene for the prion PrPC.
他和他的同事们研究了四种缺少这种蛋白基因的老鼠。
In 2003, Mead and his colleagues discovered a much more common variant of the prion gene that provides protection against prion diseases.
2003年，米德和他的同事发现了朊病毒基因更普遍的变体，可以抗御与朊病毒有关的疾病。
But other human diseases "look very similar to what we see in these mice," notes Aguzzi, who's eager to find out whether prion proteins are involved.
Aguzzi指出，还有一些人类疾病与这次我们在老鼠身上发现的状况非常相似。他将继续寻找朊病毒是否与这些人类疾病有关。
Objective Preparing specific antibody to prion protein.
目的制备针对朊蛋白的特异性抗体。
Can the "flipped" BSE priori induce the normal human prion to flip?
这种“变形的”BSE普里安能诱发正常人普里安发生改变吗？
The essence of prion (proteinaceous infectious particle) is a protein.
朊粒的本质是蛋白质。
These are quite effective in reducing the prion levels of cultured nerve cells.
它能有效降低体外培养的神经细胞内的朊病毒水平。
Researchers have struggled to determine what prion proteins normally do in the brain.
学者致力于研究朊蛋白在脑组织中起什么作用。
What is even more peculiar: exactly the same prion proteins occur in healthy animals.
更奇特的是：这种蛋白质在健康动物中也存在。
The malformed prion proteins can be deposited in the brain, thereby destroying brain tissue.
致病性的朊病毒蛋白质在脑中沉积并损伤脑组织。
So drugs that prevent this amyloid - prion coupling could be a potent weapon against Alzheimer's.
所以能防止淀粉样蛋白和朊病毒蛋白结合的药物可能会成为治疗老年痴呆症的强有力武器。
CJD is a progressive fatal neurodegenerative disorder caused by prion proteins accumulating within the neurons.
CJD是一种进行性致命性神经变性疾病，是由于朊病毒在神经元内堆积所致。
However, the prion protein in scrapie-infected brain tissue differs from normal prion protein in some of its properties.
然而，在感染羊瘙痒病的大脑组织的普利昂蛋白在某些性质上不同于一般的普利昂蛋白。
Objective To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells.
目的：研究朊蛋白106-126肽段在细胞水平上的毒性作用。
In this paper, the biological character, source and content of prion proteins in milk and milk products and their safety were reviewed.
本文对朊蛋白生物学特点、乳及乳制品中朊蛋白的来源和含量以及安全性进行了综述，以便为乳制品加工和安全评价提供参考。
Objective To study the inhibitive effect of prion protein on the formation of microtubules enhanced by microtubule-associated protein tau.
目的研究朊蛋白对微管相关蛋白介导的体外微管形成的影响。
Considering the long incubation times and often sporadic nature of prion diseases, this may be prudent but is still a topic of some discussion.
考虑到长时间的孵育时间和自然散在发生的阮病毒疾病，这个还是需要谨慎的，而如何灭活阮病毒仍然是讨论的焦点。
We should transform the traditional medical thinking model to research the mystery of prion. The appearances of prion diseases are discussed from philosophical angle.
必须转变固有的医学思维模式来看待朊病毒之谜，并从哲学角度探讨了朊病毒病的出现。
Surprisingly, according to the new research, wires coated with uninfected brain homogenate could also initiate prion disease in cell culture, which was transmissible to mice.
令人惊讶的是，根据这项新的研究，用未感染过的脑组织均浆包被的金属丝也能够在细胞培养中引发感染性朊蛋白疾病，并可使小鼠感染。
Simon Mead of the British prion research centre at University College London says the discovery of an "anti-kuru" gene is the most clear-cut evidence yet of human evolution in action.
伦敦大学学院下属英国朊病毒研究中心的西蒙·米德表示，抗库鲁病基因的发现，是人类还在不断进化最有说服力的证据。
Whereas mice with their prion-protein gene knocked out seem to be healthy, it is thought that the gene might also help to regulate the growth of stem cells in the brain and bone marrow, Pfeifer says.
然而那些被敲除了普粒子蛋白基因的老鼠看起来很健康，Pfeifer认为这个基因可能也有助于调节大脑和骨髓的干细胞的生长。
Prion is the pathogen that caused infectious spongiform encephalopathy.
朊蛋白是传染性海绵状脑病的致病蛋白。
Prion diseases affect the brains of a number of mammals, including humans.
普利子疾病能影响许多哺乳动物的大脑，包括人类。
Prion diseases are always fatal, often, however, not until months after the outbreak of the disease. As yet there is no cure.
朊病毒病是致命的，常常在发病后数月死亡，但是目前还没有有效的治疗方法。
Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.
结论：朊蛋白106- 126肽段能够诱导分化后的PC 12细胞凋亡，具有明确的毒性作用。
This article has reviewed the recent research advances on detection and diagnosis method of Prion, which is convenient for the further research.
本综述对朊病毒检测和诊断方法进行了总结，便于进一步研究工作的进行。
The Charge Nurse will check to make sure necessary supplies and equipment are at hand for the case. These are located in the Neuro Viewing Room in the Prion Precaution Cart.
护士长应核对以确定手术所需辅助材料和设备随手可得，放置在神经观片室的朊毒体防护便携箱内。
The Charge Nurse will check to make sure necessary supplies and equipment are at hand for the case. These are located in the Neuro Viewing Room in the Prion Precaution Cart.
护士长应核对以确定手术所需辅助材料和设备随手可得，放置在神经观片室的朊毒体防护便携箱内。
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