The sufferer may have to make major changes in his or her life to arrest the disease.
患者可能得对自身生活作大的调整以抑制病情。
It will not have escaped your notice that there have been some major changes in the company.
你肯定会注意到公司已经发生了一些重大的变化。
We do not own the building. Thus, it would be impossible for us to make any major changes to it.
我们不是这栋楼房的房主，因此不能对它进行大改动。
Britain, in common with many other industrialized countries, has experienced major changes over the last 100 years.
与许多其他工业化国家一样，英国在过去100年里经历了重大的变化。
Britain has experienced major changes in the last 100 years.
在过去的100年里，英国经历了很大的变化。
Two major changes—satellite and Internet radio—will force radio advertisers to adapt their methods.
两个主要的变化——卫星和网络广播——将迫使广播广告商调整他们的方法。
These developments have caused major changes like additional erosion of the Earth's surface and deforestation.
这些发展导致了重大变化，如地球表面的进一步侵蚀和森林砍伐。
Backward compatibility is maintained between major changes in libraries.
程序库的重要变化之间保持了向后兼容性。
This decoupling of the Asian-western consensus could lead to major changes.
东西方之间共识的脱钩，可能会导致重大变化。
The context for transport services and infrastructure is marked by major changes.
运输服务和基础设施的背景发生了显著的变化。
The Virtual Memory Manager (VMM) undergoes major changes for a partitioned environment.
对于分区的环境，虚拟内存管理器(VMM)经历了较大的更改。
It's a prize that could help us understand what drives major changes in Earth's climate.
其成果将帮助我们理解究竟是什么驱动了主要的全球气候变化。
One of the other major changes was in the repackaging and restructuring of the entire source code.
另一项重大变化是重新打包和组织了全部源代码。
Stern has served as commissioner for close to 30 years and has overseen major changes at the league.
斯特恩担任NBA总裁的时间已接近30年，指导联盟做出了几项重大变革。
Yahoo has to endure some major changes no matter what, but nobody seems to know what they should be.
无论如何，雅虎都将经历一场剧变，但没人知道它将走向何方。
But I think that was important because the world is not always ready and prepared for major changes.
但是我认为，这是重要的，因为这个世界并不总是做好了迎接重大改变的准备。
It repeats the processes in response to major changes in system context, goals, constraints, and risks.
该框架响应系统上下文、目标、约束和风险方面的重大更改而重复执行流程。
XNI was declared stable almost two years ago and it is not expected to undergo major changes in the future.
XNI公布差不多有两年了，一直很稳定，估计将来也不会有大的变化。
If you are planning any major changes in your business this year, you should also do a feasibility study.
如果计划在今年对你的事业做出任何重大的改变，你也应该做一些可行性研究。
For major changes to a business process, the BPEL model should be re-generated from WBM and imported into WID.
对于业务流程的重要更改，应该从WBM重新生成BPEL模型并导入到WID中。
A sharp drop in smoking has had a huge impact on heart health. And major changes in diet have also played a role.
吸烟情况的大量减少大幅度地促进了心脏健康，而对大多数饮食习惯的改变也起到了积极作用。
The transition from SLES8 to SLES9 has a few more considerations due to some of the major changes between the releases.
由于两个版本间的一些重要变化，从SLES8到SLES9的迁移需要考虑稍微更多一些事项。
One of the major changes in HTML 5 was the standardization for non-standard HTML, or more specifically, mal-formed HTML.
HTML5的重要变化之一是引入了针对非标准HTML特别是错误格式HTML的标准化解析规则。
These little changes will really add up over time, and you’ll end up with major changes in your life after a year or two.
随着时间的推移，这些小小的改变累加起来在一年或两年后就会给你的生活带来较大的变化。
Note: Samba 4, which is still under development, makes some major architectural changes, including major changes to SWAT.
注意：仍处于开发阶段的Samba4进行了一些重要的架构更改，其中包括对SWAT的重要更改。
That doesn't mean we should expect major changes in a few generations, though, evolution occurs over thousands of years.
当然，人类的进化不会在几代内完成，还是需要成千上万年的时间。
Some analysts say there is reason for Israel not to expect any major changes on the part of its traditional ally and supporter.
一些分析人士说，以色列有理由期望美国这个传统盟友和支持者不会作出任何重大改变。
Some of the major changes include easier installation, the introduction of new tools, and the standardization of installation files.
重大的改进包括简化了安装、引入了新工具和安装文件的标准化。
Note: Because we'll be making fairly major changes to portions of a Linux system, there's the real potential of messing up your system.
请注意：因为我们将对Linux系统的几个部分作出相当大的更改，所以确实可能搞糟您的系统。
LINQ is such a large and complex feature that they want to let it settle for a while before they got back and start making major changes.
LINQ是一个庞大和复杂的功能，他们希望它可以稳定一段时间再考虑是否对其进行较大的改变。
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