This century wrought major changes in our society.

本世纪给我们的社会带来了重大变革。

《牛津词典》

There were calls for major changes to the welfare system.

有人要求对福利制度进行重大改革。

《牛津词典》

The sufferer may have to make major changes in his or her life to arrest the disease.

患者可能得对自身生活作大的调整以抑制病情。

《柯林斯英汉双解大词典》

On Wednesday, President Obama proposed major changes to rebuild government supervision of the financial industry.

VOA: special.2009.06.19

There have been major changes of course in the food supply.

食品供应的进程经历了许多重大变革

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

The document was like the Constitution of the United States, but with major changes.

VOA: special.2009.07.23

Professor Richard Bedford from Population Studies Centre at the University of Waikato highlighted the major changes taking place.

UNESCO: Ethnic Diversity Broadcasting Forum, June 2009

The Bank of Japan also held a policy meeting Thursday that saw no major changes.

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Several major changes included the removal of the ice-skating rink and the creation of an atrium.

CNN: History of CNN Center