• Unlike phytochromes and phototropins, cryptochromes are not kinases.

    与植物色素和光蛋白不同,隐色素不是激酶。

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  • It functions in stoichiometric relationships forming heterotrimeric complexes with cycling and cyclin-dependent kinases.

    其功能与周期蛋白和周期蛋白依赖性激酶形成的异源三聚体存在化学计量关系。

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  • Protein kinases and phosphatases play a central role in cellular signaling.

    蛋白激酶与蛋白磷酸酶在细胞信号传递中起着重要作用。

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  • BCRABL; tyrosine kinases; inhibitors; chronic myelogenous leukemia; review.

    bcrabl;酪氨酸激酶;抑制剂;慢性粒细胞白血病;综述。

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  • Inhibiting BCR-ABL tyrosine kinases can impede the growing progress of tumors.

    抑制BCR - ABL酪氨酸激酶可有效抑制肿瘤生长。

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  • We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases.

    我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化。

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  • But you wouldn't pick this up with an assay which only measured the kinases themselves.

    不能因为是检测阵列而强调这一点,因为检测阵列仅测定蛋白激酶本身。

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  • This paper introduces the first, second and some new BCR-ABL tyrosine kinases inhibitors.

    本文介绍了第一、二代以及新近开发的BCR - ABL酪氨酸激酶抑制剂。

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  • The largest group of kinases are protein kinases, which act on and modify the activity of specific proteins.

    蛋白激酶是数量最多的一类激酶,作用和修饰特定蛋白的活性。

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  • So people will try and get some sort of gene-based test to measure the expression-mutation of these kinases.

    因此人们尝试着取得一些基因水平的测试蛋白激酶突变表达的方法。

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  • Many centrosome-related proteins and kinases have been found to regulate different steps of centrosome duplication.

    现已发现了许多中心体蛋白及与中心体复制相关的蛋白激酶,调控着中心体复制的各个步骤。

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  • Objective To study the effects of transfection of tyrosine kinases on the tumorigenesis of nasopharyngeal carcinoma.

    目的:研究酪氨酸激酶转染对鼻咽癌细胞成瘤的影响。

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  • Signalling cascades consisting of protein kinases play important roles in hormone signal transduction pathways of plants.

    蛋白质激酶的磷酸化级联放大系统在激素的信号转导中起重要作用。

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  • So far, 518 different kinases have been identified in humans and up to 30% of human proteins are modified by these kinases.

    到目前为止,已经在人体中发现了518种激酶,高达30%的人体蛋白质都是由这些激酶调节的。

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  • Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions.

    蛋白质酪氨酸在一系列细胞活动的信号转导途径中起着重要的作用。

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  • Receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCR) and ion channel receptors are main cell surface receptors.

    酪氨酸激酶型受体、G蛋白偶联受体和离子通道型受体是细胞表面三类主要受体。

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  • They used the software to read the abstracts of 186,879 papers and produced a list of the most promising kinases for experiments.

    他们通过这种软件读取了186,879份论文的摘要,生成了一个最有希望用于试验的激酶目录单。

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  • Kinases are protein switches that activate other proteins by adding a phosphate group to them via a process called phosphorylation.

    激酶是蛋白开关,它们通过一个称为磷酸化的过程将磷酸基团结合到其他蛋白上并激活这些蛋白。

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  • Both tasocitinib and Incyte's drug, INCB028050, target Janus kinases, which mediate signalling by immune-system proteins called cytokines.

    无论是tasocitinib还是Incyte的药物,INCB 028050,都是目标直指激酶,通过一种叫做细胞因子的免疫系统蛋白介导信号。

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  • Protein kinases play important roles in plant growth and development, hormone response as well as in response to abiotic and biotic stress.

    蛋白激酶在植物生长、激素调节和生物与非生物逆境胁迫反应中起着重要的作用。

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  • The result showed that 61 histidine kinases were found in the genome and 30 histidine kinases contained total conserved transmitter domain.

    结果表明:阿维链霉菌中存在61个组氨酸蛋白激酶,其中30个组氨酸蛋白激酶包含了全部的保守传递器结构域。

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  • However, further studies have indicated that they are actually DNA-damage-response kinases, regulating more than just cell-cycle checkpoints.

    进一步的研究表明它们事实上是DNA损伤-应答激酶,不仅仅是调控细胞周期的检查点。

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  • To investigate the expression and activation of mitogen-activated protein kinases in non-small cell lung cancer and its clinical significance.

    目的:探讨丝裂原活化蛋白激酶在非小细胞肺癌中的表达及其临床意义。

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  • If one is really, for instance, captivated by the biochemistry of protein kinases, you don't necessarily have to work on kinases in oncogenesis.

    比如说,如果你真正着迷于蛋白激酶生物化学,你不一定要在肿瘤学范围内研究激酶。

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  • And several attempts to carve a new target from a family of enzymes called p38 kinases have also failed, despite favourable results in animal models.

    而且多次从酶家族P38激酶中寻求新目标的尝试也失败了,尽管动物试验的结果比较积极。

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  • The signal transduction system of cyanobacteria is constituted of two-component signal transduction system and eukaryotic-type serine/threonine kinases.

    蓝藻信号转导系统主要包括二元信号转导系统和丝氨酸/苏氨酸激酶。

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  • Our tests also demonstrate that IPA-3 is highly selective for PAK1, which means that it is less likely it will also turn off other kinases unintentionally.

    我们的测试也表明,IPA - 3对PAK1有高度选择性,这意味着它是不太可能随意的关闭其他激酶。

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  • Many cancer therapeutics, such as EGFR inhibitors, target proteins that are kinases-enzymes that initiate a cascade of signals that tell cells to reproduce.

    许多癌症治疗方法,如egfr抑制因子,靶向激酶-酶蛋白,而这些蛋白能启动新号级联反应而使细胞繁殖。

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  • K protein contains multiple modules that, on one hand, bind kinases while, on the other hand, recruit chromatin, transcription, splicing and translation factors.

    蛋白包含多种分子,不但可以结合激酶,还能募集染色质、转录、剪切和翻译因子。

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  • K protein contains multiple modules that, on one hand, bind kinases while, on the other hand, recruit chromatin, transcription, splicing and translation factors.

    蛋白包含多种分子,不但可以结合激酶,还能募集染色质、转录、剪切和翻译因子。

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