The expression decrease of IGF2 may be related to adipocyte hyperplasia.
IGF 2基因表达水平的降低可能与脂肪细胞的增殖有关。
Spotting epigenetic markers like lost IGF2 in humans could be used in future cancer-prevention strategies.
确定人类表观遗传标记物在未来将可能成为预防癌症的重要策略。
Resistant cells had higher IGF2 expression compared with sensitive cells, and IGF pathway inhibition restored sensitivity to Taxol.
耐药细胞与敏感细胞相比igf2的表达更多，抑制IGF通路能恢复肿瘤细胞对紫杉醇的敏感性。
Such novel findings suggest that IGF2 represents a therapeutic target in ovarian cancer, particularly in the setting of Taxol resistance.
这些新发现提示IGF2能够成为卵巢癌的治疗靶点，特别是对那些对紫杉醇耐药的肿瘤。
Conclusions: IGF2 modulates Taxol resistance, and tumor IGF2 expression is a candidate prognostic biomarker in epithelial ovarian tumors.
结论：IGF2能够调控肿瘤细胞对紫杉醇的抵抗性，肿瘤的IGF2表达可作为判断卵巢上皮肿瘤预后的备选生物标记。
Conclusion in newborns of Chinese Han population, 21.6% showed IGF2 LOI in cord blood. IGF2 LOI may have some influences on fetal growth. Paternal age is associated with LOI.
结论汉族新生儿脐血中igf 2印迹丢失占21.6%，LOI对出生体重有一定影响，父亲年龄可能影响LOI表达。
Conclusion in newborns of Chinese Han population, 21.6% showed IGF2 LOI in cord blood. IGF2 LOI may have some influences on fetal growth. Paternal age is associated with LOI.
结论汉族新生儿脐血中igf 2印迹丢失占21.6%，LOI对出生体重有一定影响，父亲年龄可能影响LOI表达。
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