The expression decrease of IGF2 may be related to adipocyte hyperplasia.
IGF 2基因表达水平的降低可能与脂肪细胞的增殖有关。
Resistant cells had higher IGF2 expression compared with sensitive cells, and IGF pathway inhibition restored sensitivity to Taxol.
耐药细胞与敏感细胞相比igf2的表达更多，抑制IGF通路能恢复肿瘤细胞对紫杉醇的敏感性。
Conclusions: IGF2 modulates Taxol resistance, and tumor IGF2 expression is a candidate prognostic biomarker in epithelial ovarian tumors.
结论：IGF2能够调控肿瘤细胞对紫杉醇的抵抗性，肿瘤的IGF2表达可作为判断卵巢上皮肿瘤预后的备选生物标记。
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