GNAS mutations were not detected in any of the low-grade osteosarcomas from which informative DNA was extracted.
结果发现所有低级别骨肉瘤中提取的DNA均未发现GNAS突变。
The detection of GNAS mutations in primary bone tumors has been useful in clinical practice for diagnosing fibrous dysplasia.
原发性骨肿瘤中检出GNAS突变有利于临床诊断纤维性结构不良。
However, the recent report of GNAS mutations being detected in a significant proportion of parosteal osteosarcoma challenges the specificity of this mutation.
然而，最新的检测报道发现在很大一部分骨旁骨肉瘤中有GNAS突变，对该基因突变的特异性提出了质疑。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.
因此我们的研究与先前的研究一致，GNAS的突变在纤维性结构不良中有高度特异性，而在骨旁骨肉瘤和其它低级别骨肉瘤中即使有GNAS突变、也是很少的。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.
因此我们的研究与先前的研究一致，GNAS的突变在纤维性结构不良中有高度特异性，而在骨旁骨肉瘤和其它低级别骨肉瘤中即使有GNAS突变、也是很少的。
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