GNAS mutations were not detected in any of the low-grade osteosarcomas from which informative DNA was extracted.

结果发现所有低级别骨肉瘤中提取的DNA均未发现GNAS突变。

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The detection of GNAS mutations in primary bone tumors has been useful in clinical practice for diagnosing fibrous dysplasia.

原发性骨肿瘤中检出GNAS突变有利于临床诊断纤维性结构不良。

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However, the recent report of GNAS mutations being detected in a significant proportion of parosteal osteosarcoma challenges the specificity of this mutation.

然而，最新的检测报道发现在很大一部分骨旁骨肉瘤中有GNAS突变，对该基因突变的特异性提出了质疑。

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