Why did you choose this statement? Why do you not use any EGFR mutation testing on your patients?
您为什么会选择这种说法？为什么对于您的患者您不采用任何EGFR基因突变检测？
Many types of tumour produce far more EGFR than normal cells do, and one effect of that is to stimulate the proliferation of tumour cells.
许多种类的肿瘤可产生比普通细胞高得多的表皮生长因子受体，影响之一就是刺激了肿瘤细胞的扩散。
EGFR normally promotes cell growth and development, and when mutated, allows the uncontrolled growth of cells that is the hallmark of cancer.
表皮生长因子受体通常促进细胞的生长发育，一旦发生基因变异，会使细胞不受控制地生长。细胞不受控制地生长，这正是癌症的特征。
"Patients who never smoked respond better to a certain class of drugs called EGFR inhibitors, because lung cancer in these patients more often contain mutations in the EGFR gene," Rudin says.
“从不吸烟的患者对一类叫表皮生长因子受体抑制剂的药物反应更好，因为这类患者有表皮生长因子受体基因突变的可能性更大一些。”鲁丁说。
Results Normal oral mucosa was negative for EGFR.
结果正常口腔粘膜全部为阴性。
Conclusions The EGFR expression in various segment of epididymal duct is different.
结论小鼠附睾管egfr表达具有区段差异性。
The expression of EGFR and DNA ploidy in renal carcinoma has clinical significance.
研究肾癌egfr表达和DNA含量检测具有临床意义。
Objective To study the Expression and clinical significance of EGFR in ovarian cancer.
目的研究表皮生长因子受体在卵巢癌中的表达及其临床意义。
Which of the following statements best describe your attitude towards EGFR mutation testing?
下列哪种说法最能代表您对EGFR基因突变检测的看法？
The positive rate of EGFR was 40.0% in ovarian benign tumor, and was 80.0% in ovarian cancer.
EGFR在良性卵巢肿瘤组织中的阳性表达率分别为40.0%，在卵巢癌组织中的阳性表达率为80.0%；
Results EGFR was expressed both in normal chorionic villi and tissues of trophoblastic tumours.
结果EGFR在正常早孕绒毛及滋养细胞肿瘤组织均有表达。
Conclusion: It is possible to use EGFR as a candidate gene for gene therapy of malignant gliomas.
结论：EGFR有可能成为胶质瘤基因治疗的候选基因。
The results also demonstrate that EGFR signaling pathway is an important target in pancreatic cancer.
该研究也揭示了EGFR通路在胰腺癌的治疗中是一个重要的靶点。
Results Stain for EGFR was detected in all cell types of trophoblasts in GTD and normal chorion villi.
目的研究表皮生长因子受体在妊娠滋养细胞疾病的表达，探讨EGFR对预测葡萄胎恶变的价值。
Methods We analyzed 790 human glioblastomas for deletions, mutations, or expression of NFKBIA and EGFR.
方法：我们分析了790例人类胶质母细胞瘤的NFKBIA和EGFR的缺失、突变或表达。
After denaturing in urea, gradient dialysis and cleavage of GST-tag, refolded human EGFR-TKD was obtained.
经尿素变性、梯度透析复性及去除GST“标签”后，获得重折叠的人EGFR胞内酪氨酸激酶结构域蛋白。
Would you be more willing to conduct the EGFR mutation tests for your patients based on what you just read?
根据您刚才读的内容，您是否会愿意让您的患者进行EGFR突变检测？
But the tumors would start to grow again, even without EGFR, meaning something else was driving tumor growth.
但即使没有EGFR，肿瘤也可以重新生长。这暗示着还有其他因素促进肿瘤生长。
But these drugs called EGFR inhibitors, such as cetuximab, have not been very effective against colon cancer.
但这些称为EGFR抑制因子如西妥昔单抗的药物对结肠癌的治疗还不是很有效。
Intratumoral heterogeneity of EGFR protein overexpression and EGFR copy number alteration was not significant.
EGFR蛋白过表达和EGFR拷贝数改变的肿瘤内异质性无统计学意义。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
Objective: To study the expression of EGFR and PCNA protein in human gastric neoplasm and its clinical significance.
目的：研究表皮生长因子受体和增殖细胞核抗原在胃肿瘤中的表达及其临床意义。
What are the top 3 barriers to EGFR mutation testing? Why do you say that? What can help you overcome these barriers?
EGFR基因突变检测的最主要的3个障碍是什么？您为什么会这样说？怎样才能帮助您克服这些障碍呢？
Conclusions in rats with adriamycin nephrosis, EGFR can be expressed in visceral glomerular epithelia cells or podocytes.
结论阿霉素肾病大鼠的肾小球脏层上皮有egfr的表达。
A total of 2281 patients with NSCLC were screened for EGFR mutations in their tumors and, of this group, 327 had mutations.
对总共2281名NSCLC患者肿瘤组织进行EGFR变异筛查。在这些患者中，327例患者检测到变异。
Objective: To study the effect and mechanism of EGFR signaling pathway on proliferation, adhesion and invasion of A375 cells.
目的：探讨EGFR信号通路对人黑色素瘤A375细胞增殖、粘附和侵袭的影响及其分子机制。
Objective: To study the effect and mechanism of EGFR signaling pathway on proliferation, adhesion and invasion of A375 cells.
目的：探讨EGFR信号通路对人黑色素瘤A375细胞增殖、粘附和侵袭的影响及其分子机制。
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