Results Normal oral mucosa was negative for EGFR.
结果正常口腔粘膜全部为阴性。
The expression of EGFR and DNA ploidy in renal carcinoma has clinical significance.
研究肾癌egfr表达和DNA含量检测具有临床意义。
Objective To study the Expression and clinical significance of EGFR in ovarian cancer.
目的研究表皮生长因子受体在卵巢癌中的表达及其临床意义。
Which of the following statements best describe your attitude towards EGFR mutation testing?
下列哪种说法最能代表您对EGFR基因突变检测的看法？
The structures and functions of EGFR as well as current status of EGFR inhibitors are reviewed.
此文综述了EGFR的结构、功能以及EGFR抑制剂在胰腺癌治疗中的作用。
Results EGFR was expressed both in normal chorionic villi and tissues of trophoblastic tumours.
结果EGFR在正常早孕绒毛及滋养细胞肿瘤组织均有表达。
Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR).
例如，艾比特思和名为表皮生长因子受体(EGFR)的细胞表面蛋白的结合。
Why did you choose this statement? Why do you not use any EGFR mutation testing on your patients?
您为什么会选择这种说法？为什么对于您的患者您不采用任何EGFR基因突变检测？
Objective To study the relationship between HP infection and EGFR expression and gastric carcinoma.
目的探讨幽门螺杆菌感染与表皮生长因子的表达与胃癌的关系。
The results also demonstrate that EGFR signaling pathway is an important target in pancreatic cancer.
该研究也揭示了EGFR通路在胰腺癌的治疗中是一个重要的靶点。
Methods We analyzed 790 human glioblastomas for deletions, mutations, or expression of NFKBIA and EGFR.
方法：我们分析了790例人类胶质母细胞瘤的NFKBIA和EGFR的缺失、突变或表达。
But these drugs called EGFR inhibitors, such as cetuximab, have not been very effective against colon cancer.
但这些称为EGFR抑制因子如西妥昔单抗的药物对结肠癌的治疗还不是很有效。
But the tumors would start to grow again, even without EGFR, meaning something else was driving tumor growth.
但即使没有EGFR，肿瘤也可以重新生长。这暗示着还有其他因素促进肿瘤生长。
Ongoing studies focus on EGFR-TKI alone or combination chemotherapy as first line therapy in benefit population.
正在进行的临床研究聚焦于优势人群EGFR -TKI一线治疗或联合化疗的研究。
Objective: To study the expression of EGFR and PCNA protein in human gastric neoplasm and its clinical significance.
目的：研究表皮生长因子受体和增殖细胞核抗原在胃肿瘤中的表达及其临床意义。
What are the top 3 barriers to EGFR mutation testing? Why do you say that? What can help you overcome these barriers?
EGFR基因突变检测的最主要的3个障碍是什么？您为什么会这样说？怎样才能帮助您克服这些障碍呢？
Will you use for all EGFR mutation positive patients? Or only a certain proportion? What other subgroups would you use for?
对于所有的EGFR突变阳性的患者您是否都会使用？或只是一部分？那剩下的那部分您会使用什么治理方法？
A total of 2281 patients with NSCLC were screened for EGFR mutations in their tumors and, of this group, 327 had mutations.
对总共2281名NSCLC患者肿瘤组织进行EGFR变异筛查。在这些患者中，327例患者检测到变异。
Objective: To study the effect and mechanism of EGFR signaling pathway on proliferation, adhesion and invasion of A375 cells.
目的：探讨EGFR信号通路对人黑色素瘤A375细胞增殖、粘附和侵袭的影响及其分子机制。
The researchers examined individual tumors that had sidestepped or "escaped" the need for mutant EGFR to sustain their growth.
研究人员观察这些绕过或者“逃过”突变对EGFR的依赖继续生长的肿瘤。
Objective to explore the relationship between epidermal growth factor receptor (EGFR) and cell proliferation and transformation.
目的探讨表皮生长因子受体与细胞增殖、转化的关系。
In some cases, tumors that would normally have killed mice in 20 days were stable for months with the blocked expression of mutant EGFR.
在某些情况下，通常可在20天内杀死小鼠的肿瘤，在阻断突变egfr表达后在数个月内情况稳定。
Many types of tumour produce far more EGFR than normal cells do, and one effect of that is to stimulate the proliferation of tumour cells.
许多种类的肿瘤可产生比普通细胞高得多的表皮生长因子受体，影响之一就是刺激了肿瘤细胞的扩散。
Tumor biopsies were evaluated for the presence of somatic mutations in exons 18-21 of EGFR and exon 2 of RAS by bi-directional sequencing.
对肿瘤组织进行或组织检查以检测EGFR的18—21外显子的突变并应用双向测定法检测RAS的2外显子的突变。
It appears that PKC inhibitors act on similar and, in some instances, distinct pathways compared to those of the EGFR and VEGFR inhibitors.
PK C抑制剂似乎以相同的方式发挥作用，在某些情况下与那些EGFR和VEGFR抑制剂比较，却有不同的作用途径。
EGFR normally promotes cell growth and development, and when mutated, allows the uncontrolled growth of cells that is the hallmark of cancer.
表皮生长因子受体通常促进细胞的生长发育，一旦发生基因变异，会使细胞不受控制地生长。细胞不受控制地生长，这正是癌症的特征。
EGFR normally promotes cell growth and development, and when mutated, allows the uncontrolled growth of cells that is the hallmark of cancer.
表皮生长因子受体通常促进细胞的生长发育，一旦发生基因变异，会使细胞不受控制地生长。细胞不受控制地生长，这正是癌症的特征。
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