• MRP protein expression and intracellular accumulation of DNR were assayed with flow cytometry.

    流式细胞仪检测MRP蛋白表达和细胞内柔红霉素积累量。

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  • Firstly, analyze the primary Dynamic noise reduction (DNR) model, and present an improvement project.

    分析原动态降噪(DNR)模型并提出改进方案。

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  • Objective To observe the clinical effect of Daurorubicin (DNR) preventing the posterior capsule opacification (PCO).

    目的观察柔红霉素预防后囊膜混浊的临床效果。

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  • To treat rhinitis, pharyngitis, tonsillitis, glandular custody of mast, snoring and other diseases are unique by DNR.

    对DNR治疗鼻炎、咽炎、扁桃体炎、腺养体肥大、鼾症等疾病有独到之处。

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  • Both DNR accumulation reduced and DNR efflux increased in four MDR cell lines as compared with their parental cell lines.

    四株mdr细胞系与其相应敏感细胞系相比,前者对DNR的摄取均减少,外排均增加。

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  • Meanwhile, they also killed a record 14 pet dogs and another 20 bear hunting hounds last year, said DNR Warden Adrian Wydeven.

    自然资源部管理人员安德里安说,他们去年还杀死了创纪录的14只宠物狗和另外20捕熊猎狗。

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  • Conclusions: FCM is a good method to detect MDR protein and MRP function of bladder carcinoma, and DNR is a good probe to detect MRP function by FCM.

    结论:FCM是检测膀胱癌多药耐受蛋白质表达水平和MRP功能水平的好方法,DNR是FCM检测MRP功能的良好探针。

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  • Objective:To study the correlation between cytotoxicity of daunorubicine (DNR) and harringtonine (H) to leukemic cells in vitro from 39 patients with acute myeloblastic leukemia (AML).

    目的:化疗药物对急性髓性白血病细胞体外毒性进行相关性研究。

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  • Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.

    结论DNR在耐药细胞中的异常分布与肿瘤细胞耐药基因形成有关,槲皮素在体外直接抑制MRP1功能,恢复DNR在细胞内的分布。

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  • Conclusion Altered subcellular distribution of DNR in resistant cell line was related to MDR gene formation. Quercetin could inhibit MRP1 function and could restore the subcellular DNR distribution.

    结论DNR在耐药细胞中的异常分布与肿瘤细胞耐药基因形成有关,槲皮素在体外直接抑制MRP1功能,恢复DNR在细胞内的分布。

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