And if a molecule cannot cross the barrier, it will not make an effective neurological treatment.
不能通过屏障进入脑的分子当然就无法完成有效的神经治疗。
However, many classes of oligonucleotides are polyanions, so they cannot cross over cell membrane.
但是，大多数此类化合物是呈负电性的，不能有效跨越细胞膜。
You cannot cross the galaxies with a donkey. But you can cross countries and cities with plasma technology.
你不能靠驴来穿梭星系，但你可以用等离子技术跨越国家和城市。
If charge cannot cross the interface, it is said to be polarized and is electrically equivalent to a capacitor.
如果电荷不能通过这种界面，它即是极性的，其电学行为等效一个电容。
Attackers and defenders cannot cross their "restraining line" until one player from the midfield takes possession of the ball.
攻击者和捍卫者不能跨他们的“限制线”，直到一个球员从中场占有球。
Because hard links point to an inode, and inodes are only unique within a particular file system, hard links cannot cross file systems.
由于硬链接指向一个inode，且inode仅在特定文件系统内是惟一的，硬链接不能跨越文件系统。
Rule: Draw red lines match each number "1" with a "2". Lines can only go vertically or horizontally. Lines cannot cross or overlap each other or itself.
规则：在图中由数字1和2分别表示参加相亲的女士和男士，每一个女士和一个男士都将被一条红线连在一起，红线只能通过格子中心沿水平或垂直方向行进。
They don't know the exquisite operation of universe and the common source of all things. Therefore, they cannot cross over the Kunlun, nor roam in the Grand Void.
他们不了解宇宙运行之妙，也不清楚万物共同的源头，他们是无法越过昆仑山，在太虚中遨游的。
This may be because they fail to reach the part of the body where they are intended to work—many molecules, for example, cannot cross from the bloodstream into the brain.
这可能是因为这些药物不能到达预期的机体作用部位----例如很多分子不能从血流中进入大脑。
By contrast the fetus is not in a very classic inflammatory state and we know that the cytokines which are circulating in the mother cannot cross the placenta so they do not reach the fetus.
相比之下，胎儿并没有非常经典的炎症反应。我们知道，母体循环中的细胞因子并不能透过胎盘，因此不能到达胎儿。
Though people of two countries cannot go across the border without permission, animals, however, can cross the border freely.
虽然两国人民未经许可不能越过边境，但动物可以自由跨过边境。
The first relates to the question of large cross-border banks which cannot be easily dismembered into country-sized chunks.
问题之一与大型跨国银行有关。这些银行不可能轻易地按国进行分割。
This kind of cross-fertilization cannot happen without communication across departments, business units, or national borders.
这种交叉孵化作用，没有跨部门、跨产业、甚至是跨国交流的支持，如何可能发生？
Rational Rose cannot define multiple models with cross-model references that can be opened simultaneously.
RationalRose不能定义可以同时打开的具有跨模型引用的多个模型。
Similarly, Rational Rose cannot define multiple models containing cross-model references, but newer Rational software can.
类似的，RationalRose不能定义包含跨模型引用的多个模型，但较新的 Rational软件可以。
In Figure 3, I would like to fully connect five bubbles but cannot do so without having at least two lines cross each other.
在图3 中，我想将5个框全部连接起来，但如果不使至少两条线相交就无法做到这一点。 您可以看到，我没有其它方法将框3 和 5连接起来。
When legacy developers cannot easily do Web or SOA programming, and "new" developers are unable to deal with legacy code, then managing cross-technology teams is challenging and slows things down.
当旧的产品的开发人员不能很容易地进行Web和SOA编程，而“新的”开发人员也不能处理旧的代码时，管理这种混合的技术团队是富有挑战性的，并将降低开发效率。
If it cannot find a foreign key relationship between the tables, the default is a cross product.
如果查询编辑器在表之间找不到外键关系，则缺省设置为矢量积。
As a result, facial expressions that had been considered universally recognizable cannot be used to reliably convey emotion in cross-cultural situations.
因此，面部表情被认为是首要可辨认的，且在不同的文化背景下是不可以用来有效的传达情感的。
The Cross Database Chaining option cannot be set to the specified value on the specified database.
无法从数据库表中传输所有链接字段的数据。 运行“数据库向导”并重新链接形状以更正此问题。
Some people who do cross over cannot follow the Light when their mental and emotional bodies are damaged too badly and that's where your rescue circles come in so wonderfully.
一些人不能超越追随光，当他们的灵魂和情感体严重地被损坏而且那是你们的援救在如此极佳地范围开始。
The traditional management tools cannot meet the management of inter-departmental, cross-organizational and huge-information.
传统的管理手段不能适应跨部门、跨组织、信息量巨大的项目管理。
And just to give you a sense, if you do a cross-cut of this, you cannot show it from this Angle, but it should really be sort of a dumbbell shape with the nodal plane in between the two nuclei.
告诉你们这些就是给你们点概念，假如你们把他横切切开，不能从角度上展示，但它还是会保留几分哑铃的形态，以及在两核之间的节面。
Lk. 16:26 and besides all these things, between us and you a great chasm is fixed, so that those wanting to pass from here to you cannot, neither from there to us may any cross over.
路十六26不但这样，在我们与你们之间还有深渊隔定，以致人想要从这边过到你们那边是不能的，从那边越过来到我们这边也是不能的。
Lk. 16:26 and besides all these things, between us and you a great chasm is fixed, so that those wanting to pass from here to you cannot, neither from there to us may any cross over.
路十六26不但这样，在我们与你们之间还有深渊隔定，以致人想要从这边过到你们那边是不能的，从那边越过来到我们这边也是不能的。
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