有两大问题困扰有听觉障碍的人。

There are two main problems which afflict people with hearing impairments.

《柯林斯英汉双解大词典》

另一组人正在研究公司间债务这个大问题。

Another team is looking at the huge problem of debts between companies.

《柯林斯英汉双解大词典》

这是个重大问题，我们需要花较多的时间考虑。

This is a big issue ; we need more time to think about it.

《牛津词典》

对于游戏玩家来说，压力是一个大问题。

Stress is a big problem for gamers.

youdao

许多人都知道垃圾是地球上的一个大问题。

Many people know that rubbish is a big problem on planet Earth.

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我认为重大问题必须找我商量。

I expect to be consulted about major issues.

《牛津词典》

不过，确实出现了一个重大问题。

One major problem did present itself, though.

《牛津词典》

我们的计划已出了大问题。

Our plans have gone horribly wrong.

《柯林斯英汉双解大词典》

她凭直觉感到出了大问题。

She intuited that something was badly wrong.

《牛津词典》

这次实验出了大问题。

The experiment went terribly wrong.

《牛津词典》

他的工作就是要记录政治家是如何对重大问题进行投票的。

His job is to record how politicians vote on major issues.

《牛津词典》

尽管上诉法院做出了裁决，但一些重大问题悬而未决。

Despite the appeals court's decision, big questions remain unanswered.

youdao

这里面牵扯许多大问题。

There are many big things involved in this.

《新英汉大辞典》

印度和中国之间的对抗才是大问题。

The big problem, though, is India's rivalry with China.

youdao

在中国针筒的回收是个大问题。

In China, recycling is a major issue.

youdao

如此，我们都有一个大问题。

So we all have a big problem.

youdao

这可是个大问题，-挺有趣。

This is a big problem. -interesting.

youdao

获得更好的数据是个大问题。

Getting better data may be a problem, however.

youdao

但还有很多大问题存在。

But there are big issues here.

youdao

但是这确是一个大问题。

But it is a big problem.

youdao

很显然，这是个大问题。

Obviously, this is the big question.

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所以，这是一个大问题。

So this is a major problem.

youdao

但这里有一个大问题。

But there is a big problem.

youdao

然而，还有个大问题。

There was, however, a big problem.

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因此，这是个大问题。

Thus, the big problem.

youdao

清理数据是个大问题。

Data cleaning is a major issue.

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有两大问题需要面对。

There are two big issues here.

youdao

有两大问题需要面对。

There are two big issues here.

youdao