Lawlessness is a major problem.
违反法律是一个严重的问题。
Stress is a major problem of modern life.
压力是现代生活中的主要问题。
One major problem did present itself, though.
不过，确实出现了一个重大问题。
It would appear that this was a major problem.
看来这是个主要问题。
Drug abuse has long been a major problem for the authorities there.
毒品滥用长期以来一直是那里的当局的一大难题。
所以，这是一个大问题。
So, it is a problem, major problem.
因此说，这是个问题，是个主要问题。
这是一个重大的问题。
This is a major problem in the UK.
这就是英国的症结之一。
他们遇到了重大问题。
Q: Is access to drugs still a major problem?
问：药物获取目前仍然是一项重大问题么？
For some applications, this can be a major problem.
对于某些应用程序，这可能是一个主要问题。
For some applications, this may be a major problem.
对于某些应用程序，这可能是一个大问题。
Boredom is a major problem in most English classes.
厌烦情绪是大部分英语课的主要问题。
Salmonellosis is a major problem in most countries.
在大多数国家沙门氏菌病是一个主要问题。
But there's one major problem: Farms can't keep up.
但有个大问题：农场跟不上。
Vandalism is a major problem in inner city schools.
故意毁坏财物的的行为是市内学校的一个严重问题。
Internationalization is also a major problem for GWT.
国际化也是GWT的一个主要问题。
I have no major problem communicating in English.
我用英语沟通没什么大问题。
"Obesity in the United States is a major problem," he said.
“肥胖症是美国面临的一大问题，”他说。
An occasional postponement of a task is not a major problem.
偶然推迟一个任务没什么大碍。
Drought and soil erosion had long been a major problem.
干旱和水土流失一直是个老大难问题。
In our experience, this confusion is not a major problem.
在我们的经验里，这种混乱不是一个主要问题。
In fact, food waste is a major problem for the whole world.
事实上，食物浪费是个世界性大问题。
If a major problem emerges, you have no choice but to resolve it.
如果出现的是个严重的问题，你除了解决它别无选择。
The safe disposal of nuclear wastes is our current major problem.
核废料的安全处理是我们目前的一个主要问题。
In addition to the whims of regulators, piracy is also a major problem.
除了监管机构的变幻不定以外，盗版也是一个重要问题。
Another major problem is the lack of standardization in the mobile space.
另一个主要问题是，手机领域缺乏标准化。
Another major problem is the lack of standardization in the mobile space.
另一个主要问题是，手机领域缺乏标准化。
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