Immunofluorescence co-localization analysis was used to examine the synthesis and secretion of the mutant protein.
免疫荧光共定位分析用于检查突变蛋白的合成和分泌。
The drug blocks a mutant protein that causes chronic myelogenous leukemia (CML), becoming the first chemotherapy to specifically target cancer cells.
该药可以阻断引起慢性髓细胞性白血病（CML）的突变蛋白，成为第一个特异靶向癌细胞的化学药。
Using the said method to prepare 6 mutant proteins of monkey metallothionein I can obtain yield and purity similar to that in wild recombinant protein.
用本发明方法制备的猴金属硫蛋白I的六个突变体蛋白，产量与纯度均与野生型重组蛋白类似。
The researchers analyzed the function of the mutant proteins, establishing that it was the "triggering" kinase segment of the protein that was central to the enzyme's defective function.
研究人员分析了突变蛋白的功能，发现它是该蛋白激发激酶作用的部分，是酶缺矢功能的核心环节。
This mutant strain was armed with an alteration in the protein it uses to enter cells.
这个突变的菌株配有变异的蛋白质，这是其进入细胞的方式。
They have pinpointed the malfunction of the protein made by mutant forms of the gene called LRRK2 and how it affects neurons, ultimately leading to their death.
他们通过这个称为LRRK2基因的突变形式精确的了解到该蛋白的非正常功能，以及它是如何影响神经元并最终导致细胞死亡。
RESULTS: After purification the form of soluble mutant increased remarkably but the forms of dimmer and higher multimer were reduced greatly to no more than 8% of the total recombinant protein.
结果：纯化后突变蛋白的可溶性成分大幅度增加，而二聚体与多聚体显著减少至纯化后总蛋白的8 %以下。
The researchers hope that understanding more about the gene's mutations and the structure of the protein may lead to drug treatments to help ensure that mutant copies of the gene are inactive.
研究者们希望，通过对该基因突变和相关蛋白结构的深入了解可以开发出有效的药物治疗来抑制突变基因的激活。
EGFR (L858R mutant specific) (43b2) Rabbit mAb (Biotinylated) detects endogenous levels of EGFR mutant L858R protein. Careful titration of this antibody may be required to obtain optimal specificity.
(L 858r特异突变)的兔源单克隆抗体(43b2)(生物素化)能检测内源l 858r位点突变的EGFR蛋白的水平。为获得最佳特异性本抗体需要仔细滴定。
Objective: To analyse the significance and relationship between p53 gene mutation and the expression of mutant type p53 gene protein in the laryngeal carcinomas.
目的：探讨喉癌P53基因突变与突变性P 53基因蛋白表达之间的相互关系及意义。
The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.
突变型p53基因的编码蛋白不但丧失上述功能，甚至出现了促使细胞癌变的作用。
Identification of protein-protein interaction sites is essential for the mutant design and prediction of protein-protein networks.
蛋白质相互作用位点的识别对于突变设计和预测蛋白质相互作用的网络是非常重要的。
Prediction of protein-protein interaction sites is essential for mutant design and reconstruction of protein-protein interaction networks.
蛋白质相互作用位点的预测对于突变设计和蛋白质相互作用网络的重构都是至关重要的。
Biotechnology companies spend years figuring out the right combination of mutant host organism and reactor conditions to fashion a protein therapy that is safe and effective.
生物科技公司耗费数年时间，试著找出适当的突变宿主生物与反应环境组合，以得到安全有效的蛋白质治疗方法。
Objective To express the nontoxic mutant CRM197 of diphtheria toxin and study its effect as a carrier protein.
目的表达白喉毒素无毒变异体CRM197，并考察其载体作用。
Objective To express the nontoxic mutant CRM197 of diphtheria toxin and study its effect as a carrier protein.
目的表达白喉毒素无毒变异体CRM197，并考察其载体作用。
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