Took it out of the virus completely, cloned it into a plasmid, that plasmid was expressed in a foreign host, in this case it was expressed in yeast cells.

将基因从病毒中完全提取出来,并克隆制成质粒,该质粒在外来宿主中表达,此例中质粒在酵母细胞中表达

耶鲁公开课 - 生物医学工程探索课程节选

Well, if you knew a cell that could serve as a host for a virus, you could use this process of cell culture to make large quantities of virus,right?

如果你知道细胞可以变成病毒的宿主,可以用培养细胞的过程,制造大量病毒,对吧

耶鲁公开课 - 生物医学工程探索课程节选

These released particles can now go on and infect neighboring cells, they can travel in the bloodstream to infect cells at a distance and the virus spreads throughout a multicellular host.

这些释放出的病毒颗粒,可以继续感染邻近的细胞,它们可以随着血流去感染远距离的细胞,于是病毒可以在多细胞宿主体内全面扩散

耶鲁公开课 - 生物医学工程探索课程节选

We talked about host cells that are perhaps infected with a virus, displaying pieces of that virus, antigenic pieces of that virus in the context of a surface receptor called MHC-1, presenting that.

我们说到过,可能受到病毒感染的宿主细胞,表现出病毒的一部分特征,病毒的抗原部分,其表面受体称为主要组织相容性抗原-1,MHC-1负责呈递抗原

耶鲁公开课 - 生物医学工程探索课程节选

So, when the right signal is received, the right T-cell finds your host cell with a foreign virus in it, the first thing that happens is that this T-cell becomes activated and it starts reproducing, making more copies of itself.

所以 当接收到正确的信号,恰当的T细胞寻觅到,感染外源病毒的细胞时,首先发生的是,T细胞被激活并开始增殖,制造更多自身拷贝

耶鲁公开课 - 生物医学工程探索课程节选