It can't enter cells because it's too big and it's too water soluble so it can't go through cell membranes.

它的分子太大了所以无法进入细胞,而且还是水溶性的,所以它也无法穿过细胞膜

耶鲁公开课 - 生物医学工程探索课程节选

And sometimes what we do, what we want to do is have them solve problems before problems get to be too big.

所以我们做的这些，就是为了在问题发生之前就解决了。

驯服淘气的人 - SpeakingMax英语口语达人

If it's there, I'm done, if not, I keep walking down, and I only stop when I get to a place where the element I'm looking for is smaller than the value in the list., in which case I know the rest of this is too big and I can stop.

并且保持遍历,我只在当当前位置的数组元素,大于目标数时停止,这意味着剩下的元素都比目标元素大，但是其他的情况,我还是要遍历完整个数组。

麻省理工公开课 - 计算机科学及编程导论课程节选

Now this class is too big for us to have some close, intimate conversation between the 150-180, however many students there are here.

这个班级太大了以致我们不能得到结论，在150-180页之间展开深入讨论，然而学生太多了。

耶鲁公开课 - 死亡课程节选

And another five, or seven, or eight years went by, and the treasurer job became even too big of a job, and he became in charge of investor relations.

几年以后，财务主管负责的工作也很多了，他就开始负责投资关系。

斯坦福公开课 - 戴尔CEO-Michael.Dell谈创业和发展课程节选

So the big lesson of this game is-- i forgot what number we're up too-- I guess this is Lesson 4 I think.

这个博弈的重要结论,我忘了第几个了,我记得应该是第四个

耶鲁公开课 - 博弈论课程节选

We are afraid of other things too but those are big things to be afraid of.

我们也害怕其他东西,但这些是我们最害怕的。

耶鲁公开课 - 心理学导论课程节选

There's lots of night clubs that are very big out here in Hollywood that lots of celebrities go, too.

好莱坞这里有好多很大的夜店，名人们也去。

好莱坞是什么样的？ - SpeakingMax英语口语达人

Our vehicles sink into wet roads and crush dry roads because they are too big and heavy.

我们的车子因为笨重,陷入泥路中，在干道路上被压碎。

普林斯顿公开课 - 国际座谈会课程节选

And maybe we don't have to consider them all, because we can say, oh this one is going to be way too big.

可能我们不用全部考虑，因为我们可以说，哦,这大得都无法想象了。

麻省理工公开课 - 计算机科学及编程导论课程节选

Now these worries were raised by John Locke the great British philosopher, and he thought, this is too big a pill to swallow.

这是约翰·洛克提出的,他是伟大的英国哲学家，他认为，这个问题太大。

耶鲁公开课 - 死亡课程节选

This is too big a bullet to bite.

太难解决了。

耶鲁公开课 - 死亡课程节选

And that idea was, we make a guess in the middle, we test it so this is kind of a guess and check, and if the answer was too big, then we knew that we should be looking over here. If it was too small, we knew we should be looking over here, and then we would repeat.

这些有理数是有序排列的,然后我们的想法是,首先在中间取个数作为猜想数，然后对这个猜想数进行验证，如果由猜想数得到的答案太大,我们知道应该跳过，比猜想数大的那个区间，如果太小的话。

麻省理工公开课 - 计算机科学及编程导论课程节选

So leadership is kind of a big word that you see written probably too often these days, in too many newspaper articles, and it probably comes up in too many Yale classes, and I don't claim to know anything about leadership.

领导力这个大词,最近一直都很火啊,我们经常能在报章中看到它,在耶鲁大学的课堂里也能经常听到,我不敢说对领导力有多么深刻的见解

耶鲁公开课 - 博弈论课程节选

But again,all I can tell you is, I find that too big a price to pay.

但我还是再一次告诉你们，那样说的代价沉重得我无法承受。

耶鲁公开课 - 死亡课程节选