And I responded to at least one email about this issue, someone quite correctly said tuple are immutable, how can I change one?

我在不止一封邮件里回复了这个问题,一些人很明智，知道元组不可变,但是疑问怎么能去改变他们，我的答案是？

麻省理工公开课 - 计算机科学及编程导论课程节选

You know, this whole issue about, especially with what happened in Japan.

这关系到，尤其是日本发生了那样的事情。

没有智能手机活不了 - SpeakingMax英语口语达人

This issue here, October 1922, includes The Waste Land by T.S. Eliot.

922年十月的这一期，内容包括艾略特的《荒原》

耶鲁公开课 - 现代诗歌课程节选

So it turns out there's this issue of scope here.

所以结果是这里有一个范围问题。

哈佛公开课 - 计算机科学课程节选

I don't have any more philosophical arguments up my sleeve on this issue.

我已两手空空，拿不出什么哲学论调了。

耶鲁公开课 - 死亡课程节选

The second one--the second study illustrates this issue even more clearly.

第二个研究,更加清晰的对该问题进行了阐述

耶鲁公开课 - 心理学导论课程节选

Every once in a while we'll bring up an issue of well, how has this been interpreted over the centuries?

偶尔我们会提到，几个世纪以来是如何解读的？

耶鲁公开课 - 新约课程节选

The real issue is to figure out how to build constructs out of this that tackle particular problems, but the fundamental basics of computation are just captured in that set of mechanisms.

坏消息是当然这不是真的,真正的问题是怎么来,构建解决特定的问题的这些结构，但是运算的最基本的东西,仅仅体现在机制集里。

麻省理工公开课 - 计算机科学及编程导论课程节选

You've got to put more pressure on one side than the other if you want to push that gas through the throttle, right? So this is where the time scale issue comes into play.

如果你想让更多的气体通过节流阀,应该使一边的压强,大于另一边，是吗？所以这就是,时间尺度发挥作用的地方。

麻省理工公开课 - 热力学与动力学课程节选

This is a crucial issue for the Russian formalists, which they handle very boldly.

这是俄国形式主义者的重要论点，他们处理的十分大胆。

耶鲁公开课 - 文学理论导论课程节选

Hopefully, they'll all study them again, so this won't be an issue.

希望他们也都重新学一遍，这样就不会出问题。

麻省理工公开课 - 化学原理课程节选

But the fact that this type of report the goverment published itself suggest that they are thinking about it and once it becomes part of the public discourse this typle of issue... some action is likely to follow.

政府自身愿意写出这种报告,从另一角度说明,他们在思考这个问题,一旦这个问题受到公共瞩目,这类问题。,就可能有人开始动手解决。

普林斯顿公开课 - 国际座谈会课程节选

We will return to this issue later.

我们过一会再回到这个问题

耶鲁公开课 - 基础物理课程节选

Now if any of you are interested in exploring this issue of food and history there's an awful lot written about it a number of books that have been written about it that are quite good.

现在,如果谁,对探究食物与人类历史的关系有兴趣的话,有很多关于这方面的著作,很多这方面的好书

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

And there're different people who have different tastes about what you do with this piece and that piece of land how do you approach this political issue and that issue.

不同的人有不同的喜好,在应该对这一国及那一国实行何种策略的问题上,在如何解决这一以及其它政治问题上意见都不同。

普林斯顿公开课 - 人性课程节选

One more issue is, you have another decision when you run up to hit this, hit the penalty other than just left and right.

另一个问题是,在你主罚点球的时候,除了左路右路外还有别的需要考虑吗

耶鲁公开课 - 博弈论课程节选